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Assessment of Amyloid Forming Tendency of Peptide Sequences from Amyloid Beta and Tau Proteins Using Force-Field, Semi-Empirical, and Density Functional Theory Calculations

A wide variety of neurodegenerative diseases are characterized by the accumulation of protein aggregates in intraneuronal or extraneuronal brain regions. In Alzheimer’s disease (AD), the extracellular aggregates originate from amyloid-β proteins, while the intracellular aggregates are formed from mi...

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Detalles Bibliográficos
Autores principales: Muvva, Charuvaka, Murugan, Natarajan Arul, Subramanian, Venkatesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005029/
https://www.ncbi.nlm.nih.gov/pubmed/33806726
http://dx.doi.org/10.3390/ijms22063244