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Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical

Chitin (poly-N-acetyl-D-glucosamine) is the second (after cellulose) most abundant organic polymer. In its deacetylated form—chitosan—becomes a very interesting material for medical use. The chitosan nano-structures whose preparation is described in this article shows unique biomedical value. The pr...

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Autores principales: Sivanesan, Iyyakkannu, Muthu, Manikandan, Gopal, Judy, Hasan, Nazim, Kashif Ali, Syed, Shin, Juhyun, Oh, Jae-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005131/
https://www.ncbi.nlm.nih.gov/pubmed/33806968
http://dx.doi.org/10.3390/nano11030821
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author Sivanesan, Iyyakkannu
Muthu, Manikandan
Gopal, Judy
Hasan, Nazim
Kashif Ali, Syed
Shin, Juhyun
Oh, Jae-Wook
author_facet Sivanesan, Iyyakkannu
Muthu, Manikandan
Gopal, Judy
Hasan, Nazim
Kashif Ali, Syed
Shin, Juhyun
Oh, Jae-Wook
author_sort Sivanesan, Iyyakkannu
collection PubMed
description Chitin (poly-N-acetyl-D-glucosamine) is the second (after cellulose) most abundant organic polymer. In its deacetylated form—chitosan—becomes a very interesting material for medical use. The chitosan nano-structures whose preparation is described in this article shows unique biomedical value. The preparation of nanochitosan, as well as the most vital biomedical applications (antitumor, drug delivery and other medical uses), have been discussed in this review. The challenges confronting the progress of nanochitosan from benchtop to bedside clinical settings have been evaluated. The need for inclusion of nano aspects into chitosan research, with improvisation from nanotechnological inputs has been prescribed for breaking down the limitations. Future perspectives of nanochitosan and the challenges facing nanochitosan applications and the areas needing research focus have been highlighted.
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spelling pubmed-80051312021-03-29 Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical Sivanesan, Iyyakkannu Muthu, Manikandan Gopal, Judy Hasan, Nazim Kashif Ali, Syed Shin, Juhyun Oh, Jae-Wook Nanomaterials (Basel) Review Chitin (poly-N-acetyl-D-glucosamine) is the second (after cellulose) most abundant organic polymer. In its deacetylated form—chitosan—becomes a very interesting material for medical use. The chitosan nano-structures whose preparation is described in this article shows unique biomedical value. The preparation of nanochitosan, as well as the most vital biomedical applications (antitumor, drug delivery and other medical uses), have been discussed in this review. The challenges confronting the progress of nanochitosan from benchtop to bedside clinical settings have been evaluated. The need for inclusion of nano aspects into chitosan research, with improvisation from nanotechnological inputs has been prescribed for breaking down the limitations. Future perspectives of nanochitosan and the challenges facing nanochitosan applications and the areas needing research focus have been highlighted. MDPI 2021-03-23 /pmc/articles/PMC8005131/ /pubmed/33806968 http://dx.doi.org/10.3390/nano11030821 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Review
Sivanesan, Iyyakkannu
Muthu, Manikandan
Gopal, Judy
Hasan, Nazim
Kashif Ali, Syed
Shin, Juhyun
Oh, Jae-Wook
Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title_full Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title_fullStr Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title_full_unstemmed Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title_short Nanochitosan: Commemorating the Metamorphosis of an ExoSkeletal Waste to a Versatile Nutraceutical
title_sort nanochitosan: commemorating the metamorphosis of an exoskeletal waste to a versatile nutraceutical
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005131/
https://www.ncbi.nlm.nih.gov/pubmed/33806968
http://dx.doi.org/10.3390/nano11030821
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