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Impacts of injury severity on long-term outcomes following motor vehicle crashes

BACKGROUND: There is growing evidence that a range of pre-injury, injury related and post-injury factors influence social and health outcomes across the injury severity spectrum. This paper documents health related outcomes for people with mild, moderate and severe injury after motor vehicle crash (...

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Autores principales: Hung, Kevin K. C., Kifley, Annette, Brown, Katherine, Jagnoor, Jagnoor, Craig, Ashley, Gabbe, Belinda, Derrett, Sarah, Dinh, Michael, Gopinath, Bamini, Cameron, Ian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005247/
https://www.ncbi.nlm.nih.gov/pubmed/33773593
http://dx.doi.org/10.1186/s12889-021-10638-7
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author Hung, Kevin K. C.
Kifley, Annette
Brown, Katherine
Jagnoor, Jagnoor
Craig, Ashley
Gabbe, Belinda
Derrett, Sarah
Dinh, Michael
Gopinath, Bamini
Cameron, Ian D.
author_facet Hung, Kevin K. C.
Kifley, Annette
Brown, Katherine
Jagnoor, Jagnoor
Craig, Ashley
Gabbe, Belinda
Derrett, Sarah
Dinh, Michael
Gopinath, Bamini
Cameron, Ian D.
author_sort Hung, Kevin K. C.
collection PubMed
description BACKGROUND: There is growing evidence that a range of pre-injury, injury related and post-injury factors influence social and health outcomes across the injury severity spectrum. This paper documents health related outcomes for people with mild, moderate and severe injury after motor vehicle crash (MVC) injuries in New South Wales, Australia. METHODS: This inception cohort study followed 2019 people injured in MVCs, for 6 and 12 months post-injury. We categorised moderate injury as hospital length-of-stay (LOS) of 2–6 days and Injury Severity Score (ISS) of 4–11, while severe injury as LOS ≥7 days or ISS ≥ 12. We examined differences in paid work status, 12-Item Short Form Survey (SF12), EQ-5D and World Health Organisation Disability Assessment Schedule II (WHODAS) outcomes longitudinally from baseline to 12 months between levels of injury severity using linear mixed models for repeated measures. We first considered minimally sufficient adjustment factors (age, sex, crash role, perceived danger in crash, pre-injury health, pre-injury EQ-5D, recruitment source), and then more extensive adjustments including post-injury factors. The presence of mediating pathways for SF-12 Physical Component Summary (PCS) and Mental Component Summary (MCS) via post-injury factors was evaluated. RESULTS: Based on hospital length of stay (LOS), 25 and 10% of participants sustained moderate and severe injuries, respectively, while 43 and 4% had these injuries based on ISS. Twelve months post-injury LOS ≥7 days versus ≤1 day was associated with an estimated 9 units lower mean SF12 PCS using a minimally sufficient adjustment model, and LOS ≥ 7 days was associated with a 3 units lower mean SF12 MCS score. Mediation analyses (LOS ≥ 7 days vs ≤1 day) found for SF12 MCS outcomes, effects of injury severity were small and mostly indirect (direct effect − 0.03, indirect effect − 0.22). Whereas for SF12 PCS outcomes the effect of having a more severe injury rather than mild were both direct and indirect (direct effect − 0.50, indirect effect − 0.38). CONCLUSIONS: Individuals with severe injuries (those with LOS ≥ 7 days and ISS 12+) had poorer recovery 12 months after the injury. In addition, post-injury mediators have an important role in influencing long-term health outcomes. TRIAL REGISTRATION: Australia New Zealand Clinical trial registry identification number - ACTRN12613000889752. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10638-7.
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spelling pubmed-80052472021-03-30 Impacts of injury severity on long-term outcomes following motor vehicle crashes Hung, Kevin K. C. Kifley, Annette Brown, Katherine Jagnoor, Jagnoor Craig, Ashley Gabbe, Belinda Derrett, Sarah Dinh, Michael Gopinath, Bamini Cameron, Ian D. BMC Public Health Research Article BACKGROUND: There is growing evidence that a range of pre-injury, injury related and post-injury factors influence social and health outcomes across the injury severity spectrum. This paper documents health related outcomes for people with mild, moderate and severe injury after motor vehicle crash (MVC) injuries in New South Wales, Australia. METHODS: This inception cohort study followed 2019 people injured in MVCs, for 6 and 12 months post-injury. We categorised moderate injury as hospital length-of-stay (LOS) of 2–6 days and Injury Severity Score (ISS) of 4–11, while severe injury as LOS ≥7 days or ISS ≥ 12. We examined differences in paid work status, 12-Item Short Form Survey (SF12), EQ-5D and World Health Organisation Disability Assessment Schedule II (WHODAS) outcomes longitudinally from baseline to 12 months between levels of injury severity using linear mixed models for repeated measures. We first considered minimally sufficient adjustment factors (age, sex, crash role, perceived danger in crash, pre-injury health, pre-injury EQ-5D, recruitment source), and then more extensive adjustments including post-injury factors. The presence of mediating pathways for SF-12 Physical Component Summary (PCS) and Mental Component Summary (MCS) via post-injury factors was evaluated. RESULTS: Based on hospital length of stay (LOS), 25 and 10% of participants sustained moderate and severe injuries, respectively, while 43 and 4% had these injuries based on ISS. Twelve months post-injury LOS ≥7 days versus ≤1 day was associated with an estimated 9 units lower mean SF12 PCS using a minimally sufficient adjustment model, and LOS ≥ 7 days was associated with a 3 units lower mean SF12 MCS score. Mediation analyses (LOS ≥ 7 days vs ≤1 day) found for SF12 MCS outcomes, effects of injury severity were small and mostly indirect (direct effect − 0.03, indirect effect − 0.22). Whereas for SF12 PCS outcomes the effect of having a more severe injury rather than mild were both direct and indirect (direct effect − 0.50, indirect effect − 0.38). CONCLUSIONS: Individuals with severe injuries (those with LOS ≥ 7 days and ISS 12+) had poorer recovery 12 months after the injury. In addition, post-injury mediators have an important role in influencing long-term health outcomes. TRIAL REGISTRATION: Australia New Zealand Clinical trial registry identification number - ACTRN12613000889752. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10638-7. BioMed Central 2021-03-27 /pmc/articles/PMC8005247/ /pubmed/33773593 http://dx.doi.org/10.1186/s12889-021-10638-7 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Hung, Kevin K. C.
Kifley, Annette
Brown, Katherine
Jagnoor, Jagnoor
Craig, Ashley
Gabbe, Belinda
Derrett, Sarah
Dinh, Michael
Gopinath, Bamini
Cameron, Ian D.
Impacts of injury severity on long-term outcomes following motor vehicle crashes
title Impacts of injury severity on long-term outcomes following motor vehicle crashes
title_full Impacts of injury severity on long-term outcomes following motor vehicle crashes
title_fullStr Impacts of injury severity on long-term outcomes following motor vehicle crashes
title_full_unstemmed Impacts of injury severity on long-term outcomes following motor vehicle crashes
title_short Impacts of injury severity on long-term outcomes following motor vehicle crashes
title_sort impacts of injury severity on long-term outcomes following motor vehicle crashes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005247/
https://www.ncbi.nlm.nih.gov/pubmed/33773593
http://dx.doi.org/10.1186/s12889-021-10638-7
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