Cargando…
Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to constru...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Radiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005351/ https://www.ncbi.nlm.nih.gov/pubmed/33289354 http://dx.doi.org/10.3348/kjr.2020.0051 |
_version_ | 1783672109319323648 |
---|---|
author | Park, Hyoung Suk Jeon, Kiwan Cho, Yeon Jin Kim, Se Woo Lee, Seul Bi Choi, Gayoung Lee, Seunghyun Choi, Young Hun Cheon, Jung-Eun Kim, Woo Sun Ryu, Young Jin Hwang, Jae-Yeon |
author_facet | Park, Hyoung Suk Jeon, Kiwan Cho, Yeon Jin Kim, Se Woo Lee, Seul Bi Choi, Gayoung Lee, Seunghyun Choi, Young Hun Cheon, Jung-Eun Kim, Woo Sun Ryu, Young Jin Hwang, Jae-Yeon |
author_sort | Park, Hyoung Suk |
collection | PubMed |
description | OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to construct a dataset that was further divided into training (80%), validation (10%), or test sets (10%). Three radiologists were asked to label the hip images as normal or DDH. To investigate the diagnostic performance of the deep learning algorithm, we calculated the receiver operating characteristics (ROC), precision-recall curve (PRC) plots, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) and compared them with the performance of radiologists with different levels of experience. RESULTS: The area under the ROC plot generated by the deep learning algorithm and radiologists was 0.988 and 0.988–0.919, respectively. The area under the PRC plot generated by the deep learning algorithm and radiologists was 0.973 and 0.618–0.958, respectively. The sensitivity, specificity, PPV, and NPV of the proposed deep learning algorithm were 98.0, 98.1, 84.5, and 99.8%, respectively. There was no significant difference in the diagnosis of DDH by the algorithm and the radiologist with experience in pediatric radiology (p = 0.180). However, the proposed model showed higher sensitivity, specificity, and PPV, compared to the radiologist without experience in pediatric radiology (p < 0.001). CONCLUSION: The proposed deep learning algorithm provided an accurate diagnosis of DDH on hip radiographs, which was comparable to the diagnosis by an experienced radiologist. |
format | Online Article Text |
id | pubmed-8005351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Society of Radiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-80053512021-04-03 Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs Park, Hyoung Suk Jeon, Kiwan Cho, Yeon Jin Kim, Se Woo Lee, Seul Bi Choi, Gayoung Lee, Seunghyun Choi, Young Hun Cheon, Jung-Eun Kim, Woo Sun Ryu, Young Jin Hwang, Jae-Yeon Korean J Radiol Pediatric Imaging OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to construct a dataset that was further divided into training (80%), validation (10%), or test sets (10%). Three radiologists were asked to label the hip images as normal or DDH. To investigate the diagnostic performance of the deep learning algorithm, we calculated the receiver operating characteristics (ROC), precision-recall curve (PRC) plots, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) and compared them with the performance of radiologists with different levels of experience. RESULTS: The area under the ROC plot generated by the deep learning algorithm and radiologists was 0.988 and 0.988–0.919, respectively. The area under the PRC plot generated by the deep learning algorithm and radiologists was 0.973 and 0.618–0.958, respectively. The sensitivity, specificity, PPV, and NPV of the proposed deep learning algorithm were 98.0, 98.1, 84.5, and 99.8%, respectively. There was no significant difference in the diagnosis of DDH by the algorithm and the radiologist with experience in pediatric radiology (p = 0.180). However, the proposed model showed higher sensitivity, specificity, and PPV, compared to the radiologist without experience in pediatric radiology (p < 0.001). CONCLUSION: The proposed deep learning algorithm provided an accurate diagnosis of DDH on hip radiographs, which was comparable to the diagnosis by an experienced radiologist. The Korean Society of Radiology 2021-04 2020-11-26 /pmc/articles/PMC8005351/ /pubmed/33289354 http://dx.doi.org/10.3348/kjr.2020.0051 Text en Copyright © 2021 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Pediatric Imaging Park, Hyoung Suk Jeon, Kiwan Cho, Yeon Jin Kim, Se Woo Lee, Seul Bi Choi, Gayoung Lee, Seunghyun Choi, Young Hun Cheon, Jung-Eun Kim, Woo Sun Ryu, Young Jin Hwang, Jae-Yeon Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title | Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title_full | Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title_fullStr | Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title_full_unstemmed | Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title_short | Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs |
title_sort | diagnostic performance of a new convolutional neural network algorithm for detecting developmental dysplasia of the hip on anteroposterior radiographs |
topic | Pediatric Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005351/ https://www.ncbi.nlm.nih.gov/pubmed/33289354 http://dx.doi.org/10.3348/kjr.2020.0051 |
work_keys_str_mv | AT parkhyoungsuk diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT jeonkiwan diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT choyeonjin diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT kimsewoo diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT leeseulbi diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT choigayoung diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT leeseunghyun diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT choiyounghun diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT cheonjungeun diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT kimwoosun diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT ryuyoungjin diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs AT hwangjaeyeon diagnosticperformanceofanewconvolutionalneuralnetworkalgorithmfordetectingdevelopmentaldysplasiaofthehiponanteroposteriorradiographs |