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Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs

OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to constru...

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Autores principales: Park, Hyoung Suk, Jeon, Kiwan, Cho, Yeon Jin, Kim, Se Woo, Lee, Seul Bi, Choi, Gayoung, Lee, Seunghyun, Choi, Young Hun, Cheon, Jung-Eun, Kim, Woo Sun, Ryu, Young Jin, Hwang, Jae-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Radiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005351/
https://www.ncbi.nlm.nih.gov/pubmed/33289354
http://dx.doi.org/10.3348/kjr.2020.0051
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author Park, Hyoung Suk
Jeon, Kiwan
Cho, Yeon Jin
Kim, Se Woo
Lee, Seul Bi
Choi, Gayoung
Lee, Seunghyun
Choi, Young Hun
Cheon, Jung-Eun
Kim, Woo Sun
Ryu, Young Jin
Hwang, Jae-Yeon
author_facet Park, Hyoung Suk
Jeon, Kiwan
Cho, Yeon Jin
Kim, Se Woo
Lee, Seul Bi
Choi, Gayoung
Lee, Seunghyun
Choi, Young Hun
Cheon, Jung-Eun
Kim, Woo Sun
Ryu, Young Jin
Hwang, Jae-Yeon
author_sort Park, Hyoung Suk
collection PubMed
description OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to construct a dataset that was further divided into training (80%), validation (10%), or test sets (10%). Three radiologists were asked to label the hip images as normal or DDH. To investigate the diagnostic performance of the deep learning algorithm, we calculated the receiver operating characteristics (ROC), precision-recall curve (PRC) plots, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) and compared them with the performance of radiologists with different levels of experience. RESULTS: The area under the ROC plot generated by the deep learning algorithm and radiologists was 0.988 and 0.988–0.919, respectively. The area under the PRC plot generated by the deep learning algorithm and radiologists was 0.973 and 0.618–0.958, respectively. The sensitivity, specificity, PPV, and NPV of the proposed deep learning algorithm were 98.0, 98.1, 84.5, and 99.8%, respectively. There was no significant difference in the diagnosis of DDH by the algorithm and the radiologist with experience in pediatric radiology (p = 0.180). However, the proposed model showed higher sensitivity, specificity, and PPV, compared to the radiologist without experience in pediatric radiology (p < 0.001). CONCLUSION: The proposed deep learning algorithm provided an accurate diagnosis of DDH on hip radiographs, which was comparable to the diagnosis by an experienced radiologist.
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spelling pubmed-80053512021-04-03 Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs Park, Hyoung Suk Jeon, Kiwan Cho, Yeon Jin Kim, Se Woo Lee, Seul Bi Choi, Gayoung Lee, Seunghyun Choi, Young Hun Cheon, Jung-Eun Kim, Woo Sun Ryu, Young Jin Hwang, Jae-Yeon Korean J Radiol Pediatric Imaging OBJECTIVE: To evaluate the diagnostic performance of a deep learning algorithm for the automated detection of developmental dysplasia of the hip (DDH) on anteroposterior (AP) radiographs. MATERIALS AND METHODS: Of 2601 hip AP radiographs, 5076 cropped unilateral hip joint images were used to construct a dataset that was further divided into training (80%), validation (10%), or test sets (10%). Three radiologists were asked to label the hip images as normal or DDH. To investigate the diagnostic performance of the deep learning algorithm, we calculated the receiver operating characteristics (ROC), precision-recall curve (PRC) plots, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) and compared them with the performance of radiologists with different levels of experience. RESULTS: The area under the ROC plot generated by the deep learning algorithm and radiologists was 0.988 and 0.988–0.919, respectively. The area under the PRC plot generated by the deep learning algorithm and radiologists was 0.973 and 0.618–0.958, respectively. The sensitivity, specificity, PPV, and NPV of the proposed deep learning algorithm were 98.0, 98.1, 84.5, and 99.8%, respectively. There was no significant difference in the diagnosis of DDH by the algorithm and the radiologist with experience in pediatric radiology (p = 0.180). However, the proposed model showed higher sensitivity, specificity, and PPV, compared to the radiologist without experience in pediatric radiology (p < 0.001). CONCLUSION: The proposed deep learning algorithm provided an accurate diagnosis of DDH on hip radiographs, which was comparable to the diagnosis by an experienced radiologist. The Korean Society of Radiology 2021-04 2020-11-26 /pmc/articles/PMC8005351/ /pubmed/33289354 http://dx.doi.org/10.3348/kjr.2020.0051 Text en Copyright © 2021 The Korean Society of Radiology http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pediatric Imaging
Park, Hyoung Suk
Jeon, Kiwan
Cho, Yeon Jin
Kim, Se Woo
Lee, Seul Bi
Choi, Gayoung
Lee, Seunghyun
Choi, Young Hun
Cheon, Jung-Eun
Kim, Woo Sun
Ryu, Young Jin
Hwang, Jae-Yeon
Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title_full Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title_fullStr Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title_full_unstemmed Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title_short Diagnostic Performance of a New Convolutional Neural Network Algorithm for Detecting Developmental Dysplasia of the Hip on Anteroposterior Radiographs
title_sort diagnostic performance of a new convolutional neural network algorithm for detecting developmental dysplasia of the hip on anteroposterior radiographs
topic Pediatric Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005351/
https://www.ncbi.nlm.nih.gov/pubmed/33289354
http://dx.doi.org/10.3348/kjr.2020.0051
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