Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure

Recent evidence indicates that a large proportion of deaths from coronavirus disease 2019 (COVID-19) can be attributed to cardiovascular disease, including acute myocardial infarction, arrhythmias and heart failure. Indeed, severe infection increases the risk of heart failure among patients with COV...

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Autores principales: Yi, Yang, Xu, Yanan, Jiang, Haibing, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005527/
https://www.ncbi.nlm.nih.gov/pubmed/33791346
http://dx.doi.org/10.3389/fcvm.2021.629958
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author Yi, Yang
Xu, Yanan
Jiang, Haibing
Wang, Jun
author_facet Yi, Yang
Xu, Yanan
Jiang, Haibing
Wang, Jun
author_sort Yi, Yang
collection PubMed
description Recent evidence indicates that a large proportion of deaths from coronavirus disease 2019 (COVID-19) can be attributed to cardiovascular disease, including acute myocardial infarction, arrhythmias and heart failure. Indeed, severe infection increases the risk of heart failure among patients with COVID-19. In most patients, heart failure arises from complex interactions between pre-existing conditions, cardiac injury, renin-angiotensin system activation, and the effects of systemic inflammation on the cardiovascular system. In this review, we summarize current knowledge regarding pathogen-driven heart failure occurring during treatment for COVID-19, the potential effects of commonly used cardiovascular and anti-infective drugs in these patients, and possible directions for establishing a theoretical basis for clinical treatment.
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spelling pubmed-80055272021-03-30 Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure Yi, Yang Xu, Yanan Jiang, Haibing Wang, Jun Front Cardiovasc Med Cardiovascular Medicine Recent evidence indicates that a large proportion of deaths from coronavirus disease 2019 (COVID-19) can be attributed to cardiovascular disease, including acute myocardial infarction, arrhythmias and heart failure. Indeed, severe infection increases the risk of heart failure among patients with COVID-19. In most patients, heart failure arises from complex interactions between pre-existing conditions, cardiac injury, renin-angiotensin system activation, and the effects of systemic inflammation on the cardiovascular system. In this review, we summarize current knowledge regarding pathogen-driven heart failure occurring during treatment for COVID-19, the potential effects of commonly used cardiovascular and anti-infective drugs in these patients, and possible directions for establishing a theoretical basis for clinical treatment. Frontiers Media S.A. 2021-03-15 /pmc/articles/PMC8005527/ /pubmed/33791346 http://dx.doi.org/10.3389/fcvm.2021.629958 Text en Copyright © 2021 Yi, Xu, Jiang and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Yi, Yang
Xu, Yanan
Jiang, Haibing
Wang, Jun
Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title_full Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title_fullStr Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title_full_unstemmed Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title_short Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure
title_sort cardiovascular disease and covid-19: insight from cases with heart failure
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005527/
https://www.ncbi.nlm.nih.gov/pubmed/33791346
http://dx.doi.org/10.3389/fcvm.2021.629958
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