Cargando…

The Antiangiogenic Effect of Sanguinarine Chloride on Experimental Choroidal Neovacularization in Mice via Inhibiting Vascular Endothelial Growth Factor

Background: The purpose of this study is to investigate the antiangiogenic effect of Sanguinarine chloride (SC) on models of age-related macular degeneration (AMD) both in vivo and in vitro. Methods: Choroidal neovascularization (CNV) was conducted by laser photocoagulation in C57BL6/J mice. SC (2.5...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Junxiu, Mao, Ke, Gu, Qing, Wu, Xingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005541/ https://www.ncbi.nlm.nih.gov/pubmed/33790794 http://dx.doi.org/10.3389/fphar.2021.638215

Ejemplares similares

Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
por: Saeed, Mohamed E. M., et al.
Publicado: (2018)

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels
por: Fan, Fenling, et al.
Publicado: (2021)

Sanguinarine
por: Servoss, George L.
Publicado: (1910)

RGD-modified multifunctional nanoparticles encapsulating salvianolic acid A for targeted treatment of choroidal neovascularization
por: Zhang, Junxiu, et al.
Publicado: (2021)

Sanguinarine protects against ovariectomy-induced osteoporosis in mice
por: Ma, Yan, et al.
Publicado: (2017)

Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
por: Yeo, Natalie Jia Ying, et al.
Publicado: (2019)

Sanguinarine protects against indomethacin-induced small intestine injury in rats by regulating the Nrf2/NF-κB pathways
por: Lin, Xiu-lian, et al.
Publicado: (2022)

Biosynthesis of Antitumoral and Bactericidal Sanguinarine
por: García, Víctor P., et al.
Publicado: (2006)

Toxicological Effects of Berberine and Sanguinarine
por: Singh, Nitika, et al.
Publicado: (2018)

Natural compound sanguinarine chloride targets the type III secretion system of Salmonella enterica Serovar Typhimurium
por: Zhang, Yong, et al.
Publicado: (2018)

Natural compound library screening identifies Sanguinarine chloride for the treatment of SCLC by upregulating CDKN1A
por: Zhong, Mingtian, et al.
Publicado: (2022)

Natural Product Library Screens Identify Sanguinarine Chloride as a Potent Inhibitor of Telomerase Expression and Activity
por: Yan, Siyu, et al.
Publicado: (2022)

Systems pharmacology approaches for optimization of antiangiogenic therapies: challenges and opportunities
por: Sharan, Satish, et al.
Publicado: (2015)

Safety Profile of Immunotherapy Combined With Antiangiogenic Therapy in Patients With Melanoma: Analysis of Three Clinical Studies
por: Tian, Hui, et al.
Publicado: (2021)

Early ascorbic acid administration prevents vascular endothelial cell damage in septic mice
por: Madokoro, Yutaro, et al.
Publicado: (2022)

Sanguinarine Inhibits Vascular Endothelial Growth Factor Release by Generation of Reactive Oxygen Species in MCF-7 Human Mammary Adenocarcinoma Cells
por: Dong, Xian-zhe, et al.
Publicado: (2013)

Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells
por: Winter, Ursula, et al.
Publicado: (2016)

Lycopene inhibits endothelial‐to‐mesenchymal transition of choroidal vascular endothelial cells in laser‐induced mouse choroidal neovascularization
por: Li, Lele, et al.
Publicado: (2023)

Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta
por: Zhou, Zhong-Yan, et al.
Publicado: (2019)

Vascular Abnormalities and the Role of Vascular Endothelial Growth Factor in the Epileptic Brain
por: Ogaki, Ari, et al.
Publicado: (2020)

Adverse Events of Concurrent Immune Checkpoint Inhibitors and Antiangiogenic Agents: A Systematic Review
por: Gao, Ling, et al.
Publicado: (2019)

Efficacy of Antiangiogenic Drugs in the Treatment of Diabetic Macular Edema: A Bayesian Network Analysis
por: Zhang, Xuexue, et al.
Publicado: (2021)

An Update of the Sanguinarine and Benzophenanthridine Alkaloids’ Biosynthesis and Their Applications
por: Laines-Hidalgo, José Ignacio, et al.
Publicado: (2022)

Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD
por: Mao, Ke, et al.
Publicado: (2017)

AKT/PACS2 Participates in Renal Vascular Hyperpermeability by Regulating Endothelial Fatty Acid Oxidation in Diabetic Mice
por: Shu, Zhihao, et al.
Publicado: (2022)

Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors
por: Zanella, Simone, et al.
Publicado: (2019)

Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae
por: Ohnesorge, Nils, et al.
Publicado: (2019)

Corrigendum to “Salvianolic Acid A Inhibits OX-LDL Effects on Exacerbating Choroidal Neovascularization via Downregulating CYLD”
por: Mao, Ke, et al.
Publicado: (2020)

The Natural Antiangiogenic Compound AD0157 Induces Caspase-Dependent Apoptosis in Human Myeloid Leukemia Cells
por: García-Caballero, Melissa, et al.
Publicado: (2017)

Editorial: Are natural products, used as antitumoral/antiangiogenic agents, less toxic than synthetic conventional chemotherapy?
por: Nunez, Cecilia Veronica, et al.
Publicado: (2022)

Suppression of Experimental Choroidal Neovascularization by Curcumin in Mice
por: Xie, Ping, et al.
Publicado: (2012)

Mogroside V Alleviates Oocyte Meiotic Defects and Quality Deterioration in Benzo(a)pyrene-Exposed Mice
por: Sui, Lumin, et al.
Publicado: (2021)

Kaempferol, a Major Flavonoid in Ginkgo Folium, Potentiates Angiogenic Functions in Cultured Endothelial Cells by Binding to Vascular Endothelial Growth Factor
por: Hu, Wei-Hui, et al.
Publicado: (2020)

Sanguinarine synergistically potentiates aminoglycoside‐mediated bacterial killing
por: Lu, Chang, et al.
Publicado: (2022)

Targeting pulmonary vascular endothelial cells for the treatment of respiratory diseases
por: Li, Yi-Xuan, et al.
Publicado: (2022)

Aortic dissection induced by vascular endothelial growth factor inhibitors
por: Dai, Shuqi, et al.
Publicado: (2023)

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy
por: Askou, Anne Louise, et al.
Publicado: (2019)

Hydroxytyrosol Acetate Inhibits Vascular Endothelial Cell Pyroptosis via the HDAC11 Signaling Pathway in Atherosclerosis
por: Yao, Feng, et al.
Publicado: (2021)

β-Adrenergic Receptor Inhibitor and Oncolytic Herpesvirus Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects on Colorectal Cancer
por: Hu, Jiali, et al.
Publicado: (2021)

Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance
por: Friard, Jonas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9m17es071jgb5ag2l4tgvk5mkb