Cargando…

Inflammatory Markers Predict Survival in Patients With Advanced Gastric and Colorectal Cancers Receiving Anti–PD-1 Therapy

There is a lack of useful biomarkers for predicting the efficacy of anti–programmed death-1 (PD-1) therapy for advanced gastric and colorectal cancer. To address this issue, in this study we investigated the correlation between inflammatory marker expression and survival in patients with advanced ga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Xiaona, Wang, Dan, Zhang, Wenjing, Liu, Jinshuang, Liu, Chao, Li, Qingwei, Ma, Zhigang, Li, Hengzhen, Guan, Xin, Bai, Yibing, Yang, Jiani, Lou, Changjie, Li, Xiaobo, Wang, Guangyu, Li, Zhiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005614/ https://www.ncbi.nlm.nih.gov/pubmed/33791296 http://dx.doi.org/10.3389/fcell.2021.638312

Ejemplares similares

ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness
por: Cui, Ying, et al.
Publicado: (2021)

Corrigendum: ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness
por: Cui, Ying, et al.
Publicado: (2021)

Prediction scores of postoperative liver metastasis and long‐term survival of pancreatic head cancer based on the distance between the mesenteric vessels and tumor, preoperative serum carbohydrate antigen 19‐9 level, and lymph node metastasis rate
por: Jiang, Dan, et al.
Publicado: (2022)

Cellular Senescence in Sarcopenia: Possible Mechanisms and Therapeutic Potential
por: He, Yongyu, et al.
Publicado: (2022)

Immunity-Related Gene Signature Identifies Subtypes Benefitting From Adjuvant Chemotherapy or Potentially Responding to PD1/PD-L1 Blockage in Pancreatic Cancer
por: Qian, Hao, et al.
Publicado: (2021)

Novel Insights Into the Multifaceted Functions of RNA n(6)-Methyladenosine Modification in Degenerative Musculoskeletal Diseases
por: Li, Hengzhen, et al.
Publicado: (2021)

Systematic Analysis of tRNA-Derived Small RNAs Discloses New Therapeutic Targets of Caloric Restriction in Myocardial Ischemic Rats
por: Liu, Wenjing, et al.
Publicado: (2020)

Hypoxia-Induced LIN28A mRNA Promotes the Metastasis of Colon Cancer in a Protein-Coding-Independent Manner
por: Weng, Mingjiao, et al.
Publicado: (2021)

The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma
por: Wang, Haiyu, et al.
Publicado: (2020)

Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging
por: Liu, Kun, et al.
Publicado: (2022)

RNA sequencing profiling of mRNAs, long noncoding RNAs, and circular RNAs in Trigeminal Ganglion following Temporomandibular Joint inflammation
por: Liu, Xiaojun, et al.
Publicado: (2022)

MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment
por: Song, Nannan, et al.
Publicado: (2020)

Corrigendum: MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment
por: Song, Nannan, et al.
Publicado: (2020)

HCG18 Participates in Vascular Invasion of Hepatocellular Carcinoma by Regulating Macrophages and Tumor Stem Cells
por: Zhang, Liwei, et al.
Publicado: (2021)

Comprehensive Analysis of Ferroptosis Regulators With Regard to PD-L1 and Immune Infiltration in Clear Cell Renal Cell Carcinoma
por: Wang, Song, et al.
Publicado: (2021)

The Synergistic Effects of SHR6390 Combined With Pyrotinib on HER2+/HR+ Breast Cancer
por: Wang, Yukun, et al.
Publicado: (2021)

Glycolysis in tumor microenvironment as a target to improve cancer immunotherapy
por: Xiao, Chu, et al.
Publicado: (2022)

Fas-Activated Serine/Threonine Kinase Governs Cardiac Mitochondrial Complex I Functional Integrity in Ischemia/Reperfusion Heart
por: Chen, Xiyao, et al.
Publicado: (2021)

Microtubule Severing Protein Fignl2 Contributes to Endothelial and Neuronal Branching in Zebrafish Development
por: Dong, Zhangji, et al.
Publicado: (2021)

Comprehensive Analyses of MELK-Associated ceRNA Networks Reveal a Potential Biomarker for Predicting Poor Prognosis and Immunotherapy Efficacy in Hepatocellular Carcinoma
por: Liu, Yu, et al.
Publicado: (2022)

LncRNA HCP5 Induces Gastric Cancer Cell Proliferation, Invasion, and EMT Processes Through the miR-186-5p/WNT5A Axis Under Hypoxia
por: Gao, Ming, et al.
Publicado: (2021)

A Combined Two-mRNA Signature Associated With PD-L1 and Tumor Mutational Burden for Prognosis of Lung Adenocarcinoma
por: Song, Congkuan, et al.
Publicado: (2021)

Exosomal miRNA-16-5p Derived From M1 Macrophages Enhances T Cell-Dependent Immune Response by Regulating PD-L1 in Gastric Cancer
por: Li, Zhengtian, et al.
Publicado: (2020)

Genetic and Functional Characterization of Novel Brown-Like Adipocytes Around the Lamprey Brain
por: Xu, XiaoLuan, et al.
Publicado: (2021)

Combination Foretinib and Anti-PD-1 Antibody Immunotherapy for Colorectal Carcinoma
por: Fu, Yuyin, et al.
Publicado: (2021)

Comprehensive Analysis of the Immune Infiltrates and PD-L1 of m(6)A RNA Methylation Regulators in Hepatocellular Carcinoma
por: Xu, Yangtao, et al.
Publicado: (2021)

Rare BANF1 Alleles and Relatively Frequent EMD Alleles Including ‘Healthy Lipid’ Emerin p.D149H in the ExAC Cohort
por: Dharmaraj, Tejas, et al.
Publicado: (2019)

miR-212/132-Enriched Extracellular Vesicles Promote Differentiation of Induced Pluripotent Stem Cells Into Pancreatic Beta Cells
por: Bai, Chunyu, et al.
Publicado: (2021)

Corrigendum: miR-212/132-enriched extracellular vesicles promote differentiation of induced pluripotent stem cells into pancreatic beta cells
por: Bai, Chunyu, et al.
Publicado: (2023)

Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration
por: Li, Shuai, et al.
Publicado: (2021)

Analysis of DNA Repair-Related Prognostic Function and Mechanism in Gastric Cancer
por: Wang, Liqiang, et al.
Publicado: (2022)

Exosomal PD-L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies
por: Zhou, Kaijian, et al.
Publicado: (2020)

PECAM1 Combines With CXCR4 to Trigger Inflammatory Cell Infiltration and Pulpitis Progression Through Activating the NF-κB Signaling Pathway
por: Liu, Yonghong, et al.
Publicado: (2020)

Identification of the porcine IG-DMR and abnormal imprinting of DLK1-DIO3 in cloned pigs
por: Li, Junliang, et al.
Publicado: (2022)

Integration of cancer stemness and neoantigen load to predict responsiveness to anti-PD1/PDL1 therapy
por: Luo, Kunpeng, et al.
Publicado: (2022)

Identification of Uterine Microbiota in Infertile Women Receiving in vitro Fertilization With and Without Chronic Endometritis
por: Chen, Weijun, et al.
Publicado: (2021)

Augmenting the Effectiveness of CAR-T Cells by Enhanced Self-Delivery of PD-1-Neutralizing scFv
por: Ping, Yu, et al.
Publicado: (2020)

Single-Cell Transcriptomics of Cultured Amniotic Fluid Cells Reveals Complex Gene Expression Alterations in Human Fetuses With Trisomy 18
por: Wang, Jing, et al.
Publicado: (2022)

Clinical Study of 8 Cases of CHD2 Gene Mutation–Related Neurological Diseases and Their Mechanisms
por: Luo, Xiaona, et al.
Publicado: (2022)

Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors
por: Lei, Qingyang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l5dhsrmbkubhqipq1q35t07qq3