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Vitamin D3 induces mesenchymal-to-endothelial transition and promotes a proangiogenic niche through IGF-1 signaling

Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients. We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells (MSCs). VitD3 treatment increased the expression of proang...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Samanta, Anweshan, Zhao, Lin, Dudley, Nathaniel R., Buehler, Tanner, Vincent, Robert J., Hauptman, Jeryl, Girgis, Magdy, Dawn, Buddhadeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005757/
https://www.ncbi.nlm.nih.gov/pubmed/33817577
http://dx.doi.org/10.1016/j.isci.2021.102272