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Vitamin D3 induces mesenchymal-to-endothelial transition and promotes a proangiogenic niche through IGF-1 signaling
Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients. We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells (MSCs). VitD3 treatment increased the expression of proang...
Autores principales: | Chen, Lei, Samanta, Anweshan, Zhao, Lin, Dudley, Nathaniel R., Buehler, Tanner, Vincent, Robert J., Hauptman, Jeryl, Girgis, Magdy, Dawn, Buddhadeb |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005757/ https://www.ncbi.nlm.nih.gov/pubmed/33817577 http://dx.doi.org/10.1016/j.isci.2021.102272 |
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