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Conformation of the von Willebrand factor/factor VIII complex in quasi-static flow
Von Willebrand factor (VWF) is a plasma glycoprotein that circulates noncovalently bound to blood coagulation factor VIII (fVIII). VWF is a population of multimers composed of a variable number of ∼280 kDa monomers that is activated in shear flow to bind collagen and platelet glycoprotein Ibα. Elect...
Autores principales: | Parker, Ernest T., Lollar, Pete |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005835/ https://www.ncbi.nlm.nih.gov/pubmed/33600794 http://dx.doi.org/10.1016/j.jbc.2021.100420 |
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