Cargando…

Conformation of the von Willebrand factor/factor VIII complex in quasi-static flow

Von Willebrand factor (VWF) is a plasma glycoprotein that circulates noncovalently bound to blood coagulation factor VIII (fVIII). VWF is a population of multimers composed of a variable number of ∼280 kDa monomers that is activated in shear flow to bind collagen and platelet glycoprotein Ibα. Elect...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, Ernest T., Lollar, Pete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005835/
https://www.ncbi.nlm.nih.gov/pubmed/33600794
http://dx.doi.org/10.1016/j.jbc.2021.100420

Ejemplares similares