Cargando…
COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis
(1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years)...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005929/ https://www.ncbi.nlm.nih.gov/pubmed/33800304 http://dx.doi.org/10.3390/geriatrics6010025 |
_version_ | 1783672209762418688 |
---|---|
author | Thiam, Chiann Ni Hasmukharay, Kejal Lim, Wan Chieh Ng, Chai Chen Pang, Gordon Hwa Mang Abdullah, Aimy Saedon, Nor Izzati Khor, Hui Min Ong, Terence |
author_facet | Thiam, Chiann Ni Hasmukharay, Kejal Lim, Wan Chieh Ng, Chai Chen Pang, Gordon Hwa Mang Abdullah, Aimy Saedon, Nor Izzati Khor, Hui Min Ong, Terence |
author_sort | Thiam, Chiann Ni |
collection | PubMed |
description | (1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020–25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality. (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection. |
format | Online Article Text |
id | pubmed-8005929 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80059292021-03-30 COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis Thiam, Chiann Ni Hasmukharay, Kejal Lim, Wan Chieh Ng, Chai Chen Pang, Gordon Hwa Mang Abdullah, Aimy Saedon, Nor Izzati Khor, Hui Min Ong, Terence Geriatrics (Basel) Article (1) Background: Older people with COVID-19 infection report worse clinical outcomes. There is a paucity of local data and this study aimed to describe the clinical progression of older people admitted to a university hospital in Malaysia with COVID-19 infection. (2) Methods: Older people (≥60 years) admitted with COVID-19 infection confirmed with RT-PCR from 27 February 2020–25 May 2020 were included in this study. Data on patient characteristics, hospital treatment, and inpatient outcomes were collected via hospital-held electronic medical records. Analysis was done to describe the cohort and identify factors associated with inpatient mortality. (3) Results: 26 participants were included (mean age 76.2 years, female 57.7%). All had at least one comorbid condition and half were frail. About 19.2% had non-respiratory (atypical) symptoms; 23.1% had a severe disease that required intensive care unit monitoring; 46.2% were given COVID-19 targeted therapy. Inpatient mortality and overall complication rates were 23.1% and 42.3%, respectively. Delirium on presentation and lower Ct-value were associated with mortality. (4) Conclusions: Older people with COVID-19 infection have severe infection and poor hospital outcomes. Vigilant hospital care is necessary to address their multimorbidity and frailty, along with appropriate treatment for their infection. MDPI 2021-03-08 /pmc/articles/PMC8005929/ /pubmed/33800304 http://dx.doi.org/10.3390/geriatrics6010025 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Thiam, Chiann Ni Hasmukharay, Kejal Lim, Wan Chieh Ng, Chai Chen Pang, Gordon Hwa Mang Abdullah, Aimy Saedon, Nor Izzati Khor, Hui Min Ong, Terence COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title | COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title_full | COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title_fullStr | COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title_full_unstemmed | COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title_short | COVID-19 Infection among Older People Admitted to Hospital: A Cross-Sectional Analysis |
title_sort | covid-19 infection among older people admitted to hospital: a cross-sectional analysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8005929/ https://www.ncbi.nlm.nih.gov/pubmed/33800304 http://dx.doi.org/10.3390/geriatrics6010025 |
work_keys_str_mv | AT thiamchiannni covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT hasmukharaykejal covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT limwanchieh covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT ngchaichen covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT panggordonhwamang covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT abdullahaimy covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT saedonnorizzati covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT khorhuimin covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis AT ongterence covid19infectionamongolderpeopleadmittedtohospitalacrosssectionalanalysis |