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Why pancreatic islets should be regarded and regulated like organs
There are strong reasons to say that pancreatic islets are organs before they are isolated and that they should be considered to be organs once transplanted. Thus, taking into account how much we have learned about the structure and function of islet micro-organs, it seems highly illogical to on one...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006072/ https://www.ncbi.nlm.nih.gov/pubmed/33786336 http://dx.doi.org/10.32113/cellr4_20213_3083 |
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author | Weir, G. C. Bonner-Weir, S. |
author_facet | Weir, G. C. Bonner-Weir, S. |
author_sort | Weir, G. C. |
collection | PubMed |
description | There are strong reasons to say that pancreatic islets are organs before they are isolated and that they should be considered to be organs once transplanted. Thus, taking into account how much we have learned about the structure and function of islet micro-organs, it seems highly illogical to on one hand consider autologous islets be regulated as organ transplants and alloislets to be regulated with the very restrictive rules used for cell transplantation. It is particularly problematic that this policy has led to restrictions that have made it next to impossible for transplants of alloislets to be carried out in the US, which is a very sad situation for the country that made so many of the advances that brought islet transplantation to the clinic. |
format | Online Article Text |
id | pubmed-8006072 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
record_format | MEDLINE/PubMed |
spelling | pubmed-80060722021-03-29 Why pancreatic islets should be regarded and regulated like organs Weir, G. C. Bonner-Weir, S. CellR4 Repair Replace Regen Reprogram Article There are strong reasons to say that pancreatic islets are organs before they are isolated and that they should be considered to be organs once transplanted. Thus, taking into account how much we have learned about the structure and function of islet micro-organs, it seems highly illogical to on one hand consider autologous islets be regulated as organ transplants and alloislets to be regulated with the very restrictive rules used for cell transplantation. It is particularly problematic that this policy has led to restrictions that have made it next to impossible for transplants of alloislets to be carried out in the US, which is a very sad situation for the country that made so many of the advances that brought islet transplantation to the clinic. 2021-03-16 2021 /pmc/articles/PMC8006072/ /pubmed/33786336 http://dx.doi.org/10.32113/cellr4_20213_3083 Text en This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (https://creativecommons.org/licenses/by-nc-sa/4.0/) |
spellingShingle | Article Weir, G. C. Bonner-Weir, S. Why pancreatic islets should be regarded and regulated like organs |
title | Why pancreatic islets should be regarded and regulated like organs |
title_full | Why pancreatic islets should be regarded and regulated like organs |
title_fullStr | Why pancreatic islets should be regarded and regulated like organs |
title_full_unstemmed | Why pancreatic islets should be regarded and regulated like organs |
title_short | Why pancreatic islets should be regarded and regulated like organs |
title_sort | why pancreatic islets should be regarded and regulated like organs |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006072/ https://www.ncbi.nlm.nih.gov/pubmed/33786336 http://dx.doi.org/10.32113/cellr4_20213_3083 |
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