BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) regulation of β-catenin signaling in the progression of drug-induced hepatic fibrosis and carcinogenesis

BACKGROUND: BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) is a liver tumor suppressor, which is downregulated in a large number of patients with liver diseases. BRUCE facilitates DNA damage repair to protect the mouse liver against the hepatocarcinogen diethylnitrosamine (DEN)-dependent...

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Detalles Bibliográficos
Autores principales: Vilfranc, Chrystelle L, Che, Li-Xiao, Patra, Krushna C, Niu, Liang, Olowokure, Olugbenga, Wang, Jiang, Shah, Shimul A, Du, Chun-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006081/
https://www.ncbi.nlm.nih.gov/pubmed/33815677
http://dx.doi.org/10.4254/wjh.v13.i3.343

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