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Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China
BACKGROUND: The effect of the COVID-19 outbreak has led policymakers around the world to attempt transmission control. However, lockdown and shutdown interventions have caused new social problems and designating policy resumption for infection control when reopening society remains a crucial issue....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006128/ https://www.ncbi.nlm.nih.gov/pubmed/33781224 http://dx.doi.org/10.1186/s12889-021-10624-z |
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author | Ge, Yong Zhang, Wen-Bin Wang, Jianghao Liu, Mengxiao Ren, Zhoupeng Zhang, Xining Zhou, Chenghu Tian, Zhaoxing |
author_facet | Ge, Yong Zhang, Wen-Bin Wang, Jianghao Liu, Mengxiao Ren, Zhoupeng Zhang, Xining Zhou, Chenghu Tian, Zhaoxing |
author_sort | Ge, Yong |
collection | PubMed |
description | BACKGROUND: The effect of the COVID-19 outbreak has led policymakers around the world to attempt transmission control. However, lockdown and shutdown interventions have caused new social problems and designating policy resumption for infection control when reopening society remains a crucial issue. We investigated the effects of different resumption strategies on COVID-19 transmission using a modeling study setting. METHODS: We employed a susceptible-exposed-infectious-removed model to simulate COVID-19 outbreaks under five reopening strategies based on China’s business resumption progress. The effect of each strategy was evaluated using the peak values of the epidemic curves vis-à-vis confirmed active cases and cumulative cases. Two-sample t-test was performed in order to affirm that the pick values in different scenarios are different. RESULTS: We found that a hierarchy-based reopen strategy performed best when current epidemic prevention measures were maintained save for lockdown, reducing the peak number of active cases and cumulative cases by 50 and 44%, respectively. However, the modeled effect of each strategy decreased when the current intervention was lifted somewhat. Additional attention should be given to regions with significant numbers of migrants, as the potential risk of COVID-19 outbreaks amid society reopening is intrinsically high. CONCLUSIONS: Business resumption strategies have the potential to eliminate COVID-19 outbreaks amid society reopening without special control measures. The proposed resumption strategies focused mainly on decreasing the number of imported exposure cases, guaranteeing medical support for epidemic control, or decreasing active cases. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10624-z. |
format | Online Article Text |
id | pubmed-8006128 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-80061282021-03-29 Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China Ge, Yong Zhang, Wen-Bin Wang, Jianghao Liu, Mengxiao Ren, Zhoupeng Zhang, Xining Zhou, Chenghu Tian, Zhaoxing BMC Public Health Research Article BACKGROUND: The effect of the COVID-19 outbreak has led policymakers around the world to attempt transmission control. However, lockdown and shutdown interventions have caused new social problems and designating policy resumption for infection control when reopening society remains a crucial issue. We investigated the effects of different resumption strategies on COVID-19 transmission using a modeling study setting. METHODS: We employed a susceptible-exposed-infectious-removed model to simulate COVID-19 outbreaks under five reopening strategies based on China’s business resumption progress. The effect of each strategy was evaluated using the peak values of the epidemic curves vis-à-vis confirmed active cases and cumulative cases. Two-sample t-test was performed in order to affirm that the pick values in different scenarios are different. RESULTS: We found that a hierarchy-based reopen strategy performed best when current epidemic prevention measures were maintained save for lockdown, reducing the peak number of active cases and cumulative cases by 50 and 44%, respectively. However, the modeled effect of each strategy decreased when the current intervention was lifted somewhat. Additional attention should be given to regions with significant numbers of migrants, as the potential risk of COVID-19 outbreaks amid society reopening is intrinsically high. CONCLUSIONS: Business resumption strategies have the potential to eliminate COVID-19 outbreaks amid society reopening without special control measures. The proposed resumption strategies focused mainly on decreasing the number of imported exposure cases, guaranteeing medical support for epidemic control, or decreasing active cases. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10624-z. BioMed Central 2021-03-29 /pmc/articles/PMC8006128/ /pubmed/33781224 http://dx.doi.org/10.1186/s12889-021-10624-z Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Ge, Yong Zhang, Wen-Bin Wang, Jianghao Liu, Mengxiao Ren, Zhoupeng Zhang, Xining Zhou, Chenghu Tian, Zhaoxing Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title | Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title_full | Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title_fullStr | Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title_full_unstemmed | Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title_short | Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study in China |
title_sort | effect of different resumption strategies to flatten the potential covid-19 outbreaks amid society reopens: a modeling study in china |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006128/ https://www.ncbi.nlm.nih.gov/pubmed/33781224 http://dx.doi.org/10.1186/s12889-021-10624-z |
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