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Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1

Organic cation transporter 1 (OCT1) is a transporter that regulates the hepatic uptake and subsequent elimination of diverse cationic compounds. Although OCT1 has been involved in drug-drug interactions and causes pharmacokinetic variability of many prescription drugs, details of the molecular mecha...

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Detalles Bibliográficos
Autores principales: Uddin, Muhammad Erfan, Garrison, Dominique A., Kim, Kyeongmin, Jin, Yan, Eisenmann, Eric D., Huang, Kevin M., Gibson, Alice A., Hu, Zeping, Sparreboom, Alex, Hu, Shuiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006202/
https://www.ncbi.nlm.nih.gov/pubmed/33790797
http://dx.doi.org/10.3389/fphar.2021.644342