Low incidence of ABL-class and JAK-STAT signaling pathway alterations in uniformly treated pediatric and adult B-cell acute lymphoblastic leukemia patients using MRD risk-directed approach – a population-based study

BACKGROUND: ABL-class and JAK-STAT signaling pathway activating alterations have been associated with both a poor post-induction minimal residual disease (MRD) response and an inferior outcome in B-cell acute lymphoblastic leukemia (B-ALL). However, in most of the studies patients received non-unifo...

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Detalles Bibliográficos
Autores principales: Norvilas, Rimvydas, Dirse, Vaidas, Semaskeviciene, Ruta, Mickeviciute, Orinta, Gineikiene, Egle, Stoskus, Mindaugas, Vaitkeviciene, Goda, Rascon, Jelena, Griskevicius, Laimonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006339/
https://www.ncbi.nlm.nih.gov/pubmed/33781217
http://dx.doi.org/10.1186/s12885-020-07781-6

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