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Wnt Inhibition Sensitizes PD-L1 Blockade Therapy by Overcoming Bone Marrow-Derived Myofibroblasts-Mediated Immune Resistance in Tumors

Cancer-associated fibroblasts (CAFs) has been recognized as one cause of tumor resistance to immune checkpoint blockade therapy, but the underlying mechanisms still remain elusive. In the present study, a bone marrow-derived CAF (BMF) -rich tumor model is successfully established by subcutaneously m...

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Detalles Bibliográficos
Autores principales:	Huang, Tinglei, Li, Fuli, Cheng, Xiaojiao, Wang, Jianzheng, Zhang, Wenhui, Zhang, Baiwen, Tang, Yao, Li, Qingli, Zhou, Cong, Tu, Shuiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006364/ https://www.ncbi.nlm.nih.gov/pubmed/33790893 http://dx.doi.org/10.3389/fimmu.2021.619209

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