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Nucleo-cytoplasmic shuttling of murine RBPJ by Hairless protein matches that of Su(H) protein in the model system Drosophila melanogaster

ABSTRACT: CSL transcription factors are central to signal transduction in the highly conserved Notch signaling pathway. CSL acts as a molecular switch: depending on the cofactors recruited, CSL induces either activation or repression of Notch target genes. Unexpectedly, CSL depends on its cofactors...

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Detalles Bibliográficos
Autores principales: Wolf, Dorina B., Maier, Dieter, Nagel, Anja C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006372/
https://www.ncbi.nlm.nih.gov/pubmed/33775255
http://dx.doi.org/10.1186/s41065-021-00175-z