Cargando…
Nucleo-cytoplasmic shuttling of murine RBPJ by Hairless protein matches that of Su(H) protein in the model system Drosophila melanogaster
ABSTRACT: CSL transcription factors are central to signal transduction in the highly conserved Notch signaling pathway. CSL acts as a molecular switch: depending on the cofactors recruited, CSL induces either activation or repression of Notch target genes. Unexpectedly, CSL depends on its cofactors...
Autores principales: | Wolf, Dorina B., Maier, Dieter, Nagel, Anja C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006372/ https://www.ncbi.nlm.nih.gov/pubmed/33775255 http://dx.doi.org/10.1186/s41065-021-00175-z |
Ejemplares similares
-
Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster
por: Praxenthaler, Heiko, et al.
Publicado: (2015) -
Hairless-binding deficient Suppressor of Hairless alleles reveal Su(H) protein levels are dependent on complex formation with Hairless
por: Praxenthaler, Heiko, et al.
Publicado: (2017) -
An RBPJ-Drosophila Model Reveals Dependence of RBPJ Protein Stability on the Formation of Transcription–Regulator Complexes
por: Gahr, Bernd M., et al.
Publicado: (2019) -
Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster
por: Yuan, Zhenyu, et al.
Publicado: (2016) -
The tiny Hairless protein from Apis mellifera: a potent antagonist of Notch signaling in Drosophila melanogaster
por: Maier, Dieter, et al.
Publicado: (2008)