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COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020

Information on how coronavirus disease 2019 (COVID-19) mortality is related to population characteristics in low- and middle-income countries is still limited. We described the deaths from COVID-19 in Sergipe state, Northeast Brazil, from April 2 to June 27, 2020. For this purpose, we conducted a st...

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Autores principales: Martins-Filho, Paulo R., Araújo, Adriano A. S., Góes, Marco A. O., de Souza, Mércia S. F., Quintans-Júnior, Lucindo J., Martins, Natália, Santos, Victor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006401/
https://www.ncbi.nlm.nih.gov/pubmed/33791265
http://dx.doi.org/10.3389/fpubh.2021.581618
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author Martins-Filho, Paulo R.
Araújo, Adriano A. S.
Góes, Marco A. O.
de Souza, Mércia S. F.
Quintans-Júnior, Lucindo J.
Martins, Natália
Santos, Victor S.
author_facet Martins-Filho, Paulo R.
Araújo, Adriano A. S.
Góes, Marco A. O.
de Souza, Mércia S. F.
Quintans-Júnior, Lucindo J.
Martins, Natália
Santos, Victor S.
author_sort Martins-Filho, Paulo R.
collection PubMed
description Information on how coronavirus disease 2019 (COVID-19) mortality is related to population characteristics in low- and middle-income countries is still limited. We described the deaths from COVID-19 in Sergipe state, Northeast Brazil, from April 2 to June 27, 2020. For this purpose, we conducted a study composed of (i) a case series study of all deaths due to COVID-19 and (ii) a population-based study to verify the behavior of the mortality and case-fatality rates (CFR) related to COVID-19. Data from 605 deaths due to COVID-19 were used to describe the characteristics of individuals with the disease, as well as the differences in gender, age, and comorbidities. Additionally, population data were extracted to estimate the mortality and CFR by population stratum. We also performed an adjusted CFR analysis including a time lag of 14 days between the onset of symptoms and reporting deaths. Of the 605 patients included in this study, 321 (53.1%) were males and the median age was 67.0 years. Most patients (n = 447, 73.9%) who died from COVID-19 had at least one pre-existing clinical condition. The mortality rate was 29.3 deaths per 100,000 inhabitants and the crude CRF was 2.6% (95% CI 2.4–2.8). CFR was higher in males (3.1%, 95% CI 2.8–3.4; p < 0.001) and people aged ≥60 years (14.2%, 95% CI 13.0–15.6; p = 0.042). About 25% of patients died during the first 24-h post-hospital admission. The adjusted CFR for a 14-day time lag was ~2-fold higher than the crude CFR over the study period.
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spelling pubmed-80064012021-03-30 COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020 Martins-Filho, Paulo R. Araújo, Adriano A. S. Góes, Marco A. O. de Souza, Mércia S. F. Quintans-Júnior, Lucindo J. Martins, Natália Santos, Victor S. Front Public Health Public Health Information on how coronavirus disease 2019 (COVID-19) mortality is related to population characteristics in low- and middle-income countries is still limited. We described the deaths from COVID-19 in Sergipe state, Northeast Brazil, from April 2 to June 27, 2020. For this purpose, we conducted a study composed of (i) a case series study of all deaths due to COVID-19 and (ii) a population-based study to verify the behavior of the mortality and case-fatality rates (CFR) related to COVID-19. Data from 605 deaths due to COVID-19 were used to describe the characteristics of individuals with the disease, as well as the differences in gender, age, and comorbidities. Additionally, population data were extracted to estimate the mortality and CFR by population stratum. We also performed an adjusted CFR analysis including a time lag of 14 days between the onset of symptoms and reporting deaths. Of the 605 patients included in this study, 321 (53.1%) were males and the median age was 67.0 years. Most patients (n = 447, 73.9%) who died from COVID-19 had at least one pre-existing clinical condition. The mortality rate was 29.3 deaths per 100,000 inhabitants and the crude CRF was 2.6% (95% CI 2.4–2.8). CFR was higher in males (3.1%, 95% CI 2.8–3.4; p < 0.001) and people aged ≥60 years (14.2%, 95% CI 13.0–15.6; p = 0.042). About 25% of patients died during the first 24-h post-hospital admission. The adjusted CFR for a 14-day time lag was ~2-fold higher than the crude CFR over the study period. Frontiers Media S.A. 2021-03-09 /pmc/articles/PMC8006401/ /pubmed/33791265 http://dx.doi.org/10.3389/fpubh.2021.581618 Text en Copyright © 2021 Martins-Filho, Araújo, Góes, de Souza, Quintans-Júnior, Martins and Santos. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Martins-Filho, Paulo R.
Araújo, Adriano A. S.
Góes, Marco A. O.
de Souza, Mércia S. F.
Quintans-Júnior, Lucindo J.
Martins, Natália
Santos, Victor S.
COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title_full COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title_fullStr COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title_full_unstemmed COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title_short COVID-19 Mortality and Case-Fatality Rates in Sergipe State, Northeast Brazil, From April to June 2020
title_sort covid-19 mortality and case-fatality rates in sergipe state, northeast brazil, from april to june 2020
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006401/
https://www.ncbi.nlm.nih.gov/pubmed/33791265
http://dx.doi.org/10.3389/fpubh.2021.581618
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