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The TRAIL in the Treatment of Human Cancer: An Update on Clinical Trials

TRAIL (tumor-necrosis factor related apoptosis-inducing ligand, CD253) and its death receptors TRAIL-R1 and TRAIL-R2 selectively trigger the apoptotic cell death in tumor cells. For that reason, TRAIL has been extensively studied as a target of cancer therapy. In spite of the promising preclinical o...

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Detalles Bibliográficos
Autores principales:	Snajdauf, Martin, Havlova, Klara, Vachtenheim, Jiri, Ozaniak, Andrej, Lischke, Robert, Bartunkova, Jirina, Smrz, Daniel, Strizova, Zuzana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006409/ https://www.ncbi.nlm.nih.gov/pubmed/33791337 http://dx.doi.org/10.3389/fmolb.2021.628332

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