A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration

Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation (DNAm) patterns. Age and sex, two major risk factors for AD, are also known to largely affect the epigenetic profiles in brain, but their contribution to AD-associated DNAm changes has been poorly investi...

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Detalles Bibliográficos
Autores principales: Pellegrini, Camilla, Pirazzini, Chiara, Sala, Claudia, Sambati, Luisa, Yusipov, Igor, Kalyakulina, Alena, Ravaioli, Francesco, Kwiatkowska, Katarzyna M., Durso, Danielle F., Ivanchenko, Mikhail, Monti, Daniela, Lodi, Raffaele, Franceschi, Claudio, Cortelli, Pietro, Garagnani, Paolo, Bacalini, Maria Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006465/
https://www.ncbi.nlm.nih.gov/pubmed/33790779
http://dx.doi.org/10.3389/fnagi.2021.639428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006465/
https://www.ncbi.nlm.nih.gov/pubmed/33790779
http://dx.doi.org/10.3389/fnagi.2021.639428

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