Doxorubicin‐induced and trastuzumab‐induced cardiotoxicity in mice is not prevented by metoprolol

AIMS: Our objectives were to validate a murine model of chronic cardiotoxicity induced by Doxorubicin (Dox) and Trastuzumab (Trast) and to test the potential cardio‐protective effect of metoprolol. METHODS AND RESULTS: Male C57Bl6 mice were intraperitoneally injected during 2 weeks with Dox (24 mg/k...

Descripción completa

Detalles Bibliográficos
Autores principales: Nicol, Martin, Sadoune, Malha, Polidano, Evelyne, Launay, Jean Marie, Samuel, Jane Lise, Azibani, Feriel, Cohen‐Solal, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006653/
https://www.ncbi.nlm.nih.gov/pubmed/33529501
http://dx.doi.org/10.1002/ehf2.13198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006653/
https://www.ncbi.nlm.nih.gov/pubmed/33529501
http://dx.doi.org/10.1002/ehf2.13198

Ejemplares similares