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Doxorubicin‐induced and trastuzumab‐induced cardiotoxicity in mice is not prevented by metoprolol
AIMS: Our objectives were to validate a murine model of chronic cardiotoxicity induced by Doxorubicin (Dox) and Trastuzumab (Trast) and to test the potential cardio‐protective effect of metoprolol. METHODS AND RESULTS: Male C57Bl6 mice were intraperitoneally injected during 2 weeks with Dox (24 mg/k...
Autores principales: | Nicol, Martin, Sadoune, Malha, Polidano, Evelyne, Launay, Jean Marie, Samuel, Jane Lise, Azibani, Feriel, Cohen‐Solal, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006653/ https://www.ncbi.nlm.nih.gov/pubmed/33529501 http://dx.doi.org/10.1002/ehf2.13198 |
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