Cargando…

Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis

Since the establishment of highly active antiretroviral therapy, survival rates have improved among patients with human immunodeficiency virus infection giving them the possibility to become transplant candidates. Recent publications revealed that human immunodeficiency virus‐positive heart transpla...

Descripción completa

Detalles Bibliográficos
Autores principales: Szakal‐Toth, Zsofia, Szlavik, Janos, Soltesz, Adam, Berzsenyi, Viktor, Csikos, Gergely, Varga, Tamas, Racz, Kristof, Kiraly, Akos, Sax, Balazs, Hartyanszky, Istvan, Fintha, Attila, Prohaszka, Zoltan, Monostory, Katalin, Merkely, Bela, Nemeth, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006693/
https://www.ncbi.nlm.nih.gov/pubmed/33634606
http://dx.doi.org/10.1002/ehf2.13271
_version_ 1783672357601148928
author Szakal‐Toth, Zsofia
Szlavik, Janos
Soltesz, Adam
Berzsenyi, Viktor
Csikos, Gergely
Varga, Tamas
Racz, Kristof
Kiraly, Akos
Sax, Balazs
Hartyanszky, Istvan
Fintha, Attila
Prohaszka, Zoltan
Monostory, Katalin
Merkely, Bela
Nemeth, Endre
author_facet Szakal‐Toth, Zsofia
Szlavik, Janos
Soltesz, Adam
Berzsenyi, Viktor
Csikos, Gergely
Varga, Tamas
Racz, Kristof
Kiraly, Akos
Sax, Balazs
Hartyanszky, Istvan
Fintha, Attila
Prohaszka, Zoltan
Monostory, Katalin
Merkely, Bela
Nemeth, Endre
author_sort Szakal‐Toth, Zsofia
collection PubMed
description Since the establishment of highly active antiretroviral therapy, survival rates have improved among patients with human immunodeficiency virus infection giving them the possibility to become transplant candidates. Recent publications revealed that human immunodeficiency virus‐positive heart transplant recipients' survival is similar to non‐infected patients. We present the case of a 40‐year‐old human immunodeficiency virus infected patient, who was hospitalized due to severely decreased left ventricular function with a possible aetiology of acute myocarditis, that has later been confirmed by histological investigation of myocardial biopsy. Due to rapid progression to refractory cardiogenic shock, extracorporeal membrane oxygenation implantation had been initiated, which was upgraded to biventricular assist device later. On the 35th day of upgraded support, the patient underwent heart transplantation uneventfully. Our clinical experience confirms that implementation of temporary mechanical circulatory support and subsequent cardiac transplantation might be successful in human immunodeficiency virus‐positive patients even in case of new onset, irreversible acute heart failure.
format Online
Article
Text
id pubmed-8006693
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-80066932021-04-01 Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis Szakal‐Toth, Zsofia Szlavik, Janos Soltesz, Adam Berzsenyi, Viktor Csikos, Gergely Varga, Tamas Racz, Kristof Kiraly, Akos Sax, Balazs Hartyanszky, Istvan Fintha, Attila Prohaszka, Zoltan Monostory, Katalin Merkely, Bela Nemeth, Endre ESC Heart Fail Case Reports Since the establishment of highly active antiretroviral therapy, survival rates have improved among patients with human immunodeficiency virus infection giving them the possibility to become transplant candidates. Recent publications revealed that human immunodeficiency virus‐positive heart transplant recipients' survival is similar to non‐infected patients. We present the case of a 40‐year‐old human immunodeficiency virus infected patient, who was hospitalized due to severely decreased left ventricular function with a possible aetiology of acute myocarditis, that has later been confirmed by histological investigation of myocardial biopsy. Due to rapid progression to refractory cardiogenic shock, extracorporeal membrane oxygenation implantation had been initiated, which was upgraded to biventricular assist device later. On the 35th day of upgraded support, the patient underwent heart transplantation uneventfully. Our clinical experience confirms that implementation of temporary mechanical circulatory support and subsequent cardiac transplantation might be successful in human immunodeficiency virus‐positive patients even in case of new onset, irreversible acute heart failure. John Wiley and Sons Inc. 2021-02-25 /pmc/articles/PMC8006693/ /pubmed/33634606 http://dx.doi.org/10.1002/ehf2.13271 Text en © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Szakal‐Toth, Zsofia
Szlavik, Janos
Soltesz, Adam
Berzsenyi, Viktor
Csikos, Gergely
Varga, Tamas
Racz, Kristof
Kiraly, Akos
Sax, Balazs
Hartyanszky, Istvan
Fintha, Attila
Prohaszka, Zoltan
Monostory, Katalin
Merkely, Bela
Nemeth, Endre
Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title_full Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title_fullStr Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title_full_unstemmed Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title_short Acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
title_sort acute heart transplantation from mechanical circulatory support in a human immunodeficiency virus‐positive patient with fulminant myocarditis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006693/
https://www.ncbi.nlm.nih.gov/pubmed/33634606
http://dx.doi.org/10.1002/ehf2.13271
work_keys_str_mv AT szakaltothzsofia acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT szlavikjanos acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT solteszadam acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT berzsenyiviktor acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT csikosgergely acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT vargatamas acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT raczkristof acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT kiralyakos acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT saxbalazs acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT hartyanszkyistvan acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT finthaattila acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT prohaszkazoltan acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT monostorykatalin acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT merkelybela acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis
AT nemethendre acutehearttransplantationfrommechanicalcirculatorysupportinahumanimmunodeficiencyviruspositivepatientwithfulminantmyocarditis