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Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study

PURPOSE: To assess the prevalence of post-COVID symptoms in patients with recovered COVID-19 (nasopharyngeal RT PCR negative) who were discharged from an acute COVID care facility at a tertiary care teaching hospital in North India. METHODS: This study was an observational study with retrospective d...

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Autores principales: Tomar, Balvir S, Singh, Mahaveer, Nathiya, Deepak, Sharma, Abhishek, Sharma, Eshan, Bareth, Hemant, Suman, Supriya, Ruparelia, Darshan Purshotambhai, Patel, Jaykumar Bharatbhai, Gajera, Vikrant Kantilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006813/
https://www.ncbi.nlm.nih.gov/pubmed/33790636
http://dx.doi.org/10.2147/IJGM.S295499
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author Tomar, Balvir S
Singh, Mahaveer
Nathiya, Deepak
Sharma, Abhishek
Sharma, Eshan
Bareth, Hemant
Suman, Supriya
Ruparelia, Darshan Purshotambhai
Patel, Jaykumar Bharatbhai
Gajera, Vikrant Kantilal
author_facet Tomar, Balvir S
Singh, Mahaveer
Nathiya, Deepak
Sharma, Abhishek
Sharma, Eshan
Bareth, Hemant
Suman, Supriya
Ruparelia, Darshan Purshotambhai
Patel, Jaykumar Bharatbhai
Gajera, Vikrant Kantilal
author_sort Tomar, Balvir S
collection PubMed
description PURPOSE: To assess the prevalence of post-COVID symptoms in patients with recovered COVID-19 (nasopharyngeal RT PCR negative) who were discharged from an acute COVID care facility at a tertiary care teaching hospital in North India. METHODS: This study was an observational study with retrospective data collection, conducted in the COVID follow-up clinic, a combined clinic of medicine and endocrinology. Patients discharged from the acute COVID care facility were recruited after 14 days of discharge if they fulfilled inclusion and exclusion criteria. The retrospective data was collected from the hospital records/EMR and analysed by the SPSSv23. RESULTS: Fifty patients, who fulfilled the inclusion and exclusion criteria, were included in the study. The Mean age of patients was 53.4±13.8 years (range 28–77). Seventy six percent were male, and 38% had type 2 diabetes. Fever (94%), cough (78%) and breathlessness (68%), were the most common symptoms at presentation to acute care facility. Oxygen saturation at presentation had a negative correlation with D-Dimer, age, and C reactive protein. When patients were evaluated clinically, after 14 days (range 15 to 50 days) of the discharge, 82% of patients had at least one persistent symptom. Fatigue (74%) was the most common symptoms in follow-up followed by breathlessness (44%), and muscle weakness (36%). Two patients had persistent fever, even after negative RT PCR status. CONCLUSION: Patients discharged from the acute COVID care facility had a high prevalence of post-COVID symptoms even after 14 days.
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spelling pubmed-80068132021-03-30 Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study Tomar, Balvir S Singh, Mahaveer Nathiya, Deepak Sharma, Abhishek Sharma, Eshan Bareth, Hemant Suman, Supriya Ruparelia, Darshan Purshotambhai Patel, Jaykumar Bharatbhai Gajera, Vikrant Kantilal Int J Gen Med Original Research PURPOSE: To assess the prevalence of post-COVID symptoms in patients with recovered COVID-19 (nasopharyngeal RT PCR negative) who were discharged from an acute COVID care facility at a tertiary care teaching hospital in North India. METHODS: This study was an observational study with retrospective data collection, conducted in the COVID follow-up clinic, a combined clinic of medicine and endocrinology. Patients discharged from the acute COVID care facility were recruited after 14 days of discharge if they fulfilled inclusion and exclusion criteria. The retrospective data was collected from the hospital records/EMR and analysed by the SPSSv23. RESULTS: Fifty patients, who fulfilled the inclusion and exclusion criteria, were included in the study. The Mean age of patients was 53.4±13.8 years (range 28–77). Seventy six percent were male, and 38% had type 2 diabetes. Fever (94%), cough (78%) and breathlessness (68%), were the most common symptoms at presentation to acute care facility. Oxygen saturation at presentation had a negative correlation with D-Dimer, age, and C reactive protein. When patients were evaluated clinically, after 14 days (range 15 to 50 days) of the discharge, 82% of patients had at least one persistent symptom. Fatigue (74%) was the most common symptoms in follow-up followed by breathlessness (44%), and muscle weakness (36%). Two patients had persistent fever, even after negative RT PCR status. CONCLUSION: Patients discharged from the acute COVID care facility had a high prevalence of post-COVID symptoms even after 14 days. Dove 2021-03-25 /pmc/articles/PMC8006813/ /pubmed/33790636 http://dx.doi.org/10.2147/IJGM.S295499 Text en © 2021 Tomar et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Tomar, Balvir S
Singh, Mahaveer
Nathiya, Deepak
Sharma, Abhishek
Sharma, Eshan
Bareth, Hemant
Suman, Supriya
Ruparelia, Darshan Purshotambhai
Patel, Jaykumar Bharatbhai
Gajera, Vikrant Kantilal
Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title_full Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title_fullStr Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title_full_unstemmed Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title_short Prevalence of Symptoms in Patients Discharged from COVID Care Facility of NIMS Hospital: Is RT PCR Negativity Truly Reflecting Recovery? A Single-Centre Observational Study
title_sort prevalence of symptoms in patients discharged from covid care facility of nims hospital: is rt pcr negativity truly reflecting recovery? a single-centre observational study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006813/
https://www.ncbi.nlm.nih.gov/pubmed/33790636
http://dx.doi.org/10.2147/IJGM.S295499
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