Cargando…

Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration

Ezrin, radixin, and moesin (ERM) family proteins regulate cytoskeletal responses by tethering the plasma membrane to the underlying actin cortex. Mutations in ERM proteins lead to severe combined immunodeficiency, but the function of these proteins in T cells remains poorly defined. Using mice in wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Robertson, Tanner F., Chengappa, Pragati, Gomez Atria, Daniela, Wu, Christine F., Avery, Lyndsay, Roy, Nathan H., Maillard, Ivan, Petrie, Ryan J., Burkhardt, Janis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8006814/
https://www.ncbi.nlm.nih.gov/pubmed/33764397
http://dx.doi.org/10.1083/jcb.202007182