Cargando…

An evolutionarily diverged mitochondrial protein controls biofilm growth and virulence in Candida albicans

A forward genetic screening approach identified orf19.2500 as a gene controlling Candida albicans biofilm dispersal and biofilm detachment. Three-dimensional (3D) protein modeling and bioinformatics revealed that orf19.2500 is a conserved mitochondrial protein, structurally similar to, but functiona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mamouei, Zeinab, Singh, Shakti, Lemire, Bernard, Gu, Yiyou, Alqarihi, Abdullah, Nabeela, Sunna, Li, Dongmei, Ibrahim, Ashraf, Uppuluri, Priya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007014/ https://www.ncbi.nlm.nih.gov/pubmed/33720927 http://dx.doi.org/10.1371/journal.pbio.3000957

Ejemplares similares

Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis
por: Sutar, Yogesh, et al.
Publicado: (2022)

Antibodies targeting Candida albicans Als3 and Hyr1 antigens protect neonatal mice from candidiasis
por: Singh, Shakti, et al.
Publicado: (2022)

The NDV-3A vaccine protects mice from multidrug resistant Candida auris infection
por: Singh, Shakti, et al.
Publicado: (2019)

Alexidine Dihydrochloride Has Broad-Spectrum Activities against Diverse Fungal Pathogens
por: Mamouei, Zeinab, et al.
Publicado: (2018)

NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice
por: Alqarihi, Abdullah, et al.
Publicado: (2019)

574. Antibodies Targeting Candida albicans Als3 and Hyr1 Antigens Protect Neonatal Mice from Candidiasis
por: Singh, Shakti, et al.
Publicado: (2022)

Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis
por: Alkhazraji, Sondus, et al.
Publicado: (2020)

Development of a High-Throughput Candida albicans Biofilm Chip
por: Srinivasan, Anand, et al.
Publicado: (2011)

678. Galactomannan Is a Biomarker of APX001 (Fosmanogepix) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis
por: Gebremariam, Teklegiorgis, et al.
Publicado: (2019)

726. APX001 (Fosmanogepix) Is Effective in an Immunosuppressed Mouse Model of Rhizopus oryzae Infection
por: Gebremariam, Teklegiorgis, et al.
Publicado: (2019)

Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis
por: Nabeela, Sunna, et al.
Publicado: (2022)

Metabolic Profiling of Candida auris, a Newly-Emerging Multi-Drug Resistant Candida Species, by GC-MS
por: Semreen, Mohammad H., et al.
Publicado: (2019)

1724. Plasmid-free CRISPR-Cas9 System for Genetic Engineering of Rhizopus delemar
por: Gu, Yiyou, et al.
Publicado: (2019)

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle
por: Uppuluri, Priya, et al.
Publicado: (2010)

Candida albicans Dispersed Cells Are Developmentally Distinct from Biofilm and Planktonic Cells
por: Uppuluri, Priya, et al.
Publicado: (2018)

Candida auris Biofilm Colonization on Skin Niche Conditions
por: Uppuluri, Priya
Publicado: (2020)

Modulation of Candida albicans virulence in in vitro biofilms by oral bacteria
por: Morse, D.J., et al.
Publicado: (2019)

The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection
por: Uppuluri, Priya, et al.
Publicado: (2018)

Monoclonal IgM Antibodies Targeting Candida albicans Hyr1 Provide Cross-Kingdom Protection Against Gram-Negative Bacteria
por: Youssef, Eman G., et al.
Publicado: (2020)

Galactomannan Is a Biomarker of Fosmanogepix (APX001) Efficacy in Treating Experimental Invasive Pulmonary Aspergillosis
por: Gebremariam, Teclegiorgis, et al.
Publicado: (2019)

Pathogenesis and virulence of Candida albicans
por: Lopes, José Pedro, et al.
Publicado: (2021)

Streptococcus mutans Can Modulate Biofilm Formation and Attenuate the Virulence of Candida albicans
por: Barbosa, Júnia Oliveira, et al.
Publicado: (2016)

Pathogenesis and Virulence of Candida albicans and Candida glabrata
por: Henriques, Mariana, et al.
Publicado: (2020)

Phosphate in Virulence of Candida albicans and Candida glabrata
por: Köhler, Julia R., et al.
Publicado: (2020)

119. A Humanized Antibody Targeting the CotH Invasins is Protective Against Murine Mucormycosis
por: Gu, Yiyou, et al.
Publicado: (2021)

Piperine Impedes Biofilm Formation and Hyphal Morphogenesis of Candida albicans
por: Priya, Arumugam, et al.
Publicado: (2020)

Decreasing Cell Population of Individual Candida Species Does Not Impair the Virulence of Candida albicans and Candida glabrata Mixed Biofilms
por: Li, Qianqian, et al.
Publicado: (2019)

Multi-species biofilm of Candida albicans and non-Candida albicans Candida species on acrylic substrate
por: K PATHAK, Apurva, et al.
Publicado: (2012)

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence
por: Liu, Ning-Ning, et al.
Publicado: (2018)

The Role of Candida albicans Virulence Factors in the Formation of Multispecies Biofilms With Bacterial Periodontal Pathogens
por: Satala, Dorota, et al.
Publicado: (2022)

Associations of Rap1 with Cell Wall Integrity, Biofilm Formation, and Virulence in Candida albicans
por: Wang, Wen-Han, et al.
Publicado: (2022)

Characterization of Mucosal Candida albicans Biofilms
por: Dongari-Bagtzoglou, Anna, et al.
Publicado: (2009)

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis
por: Alqarihi, Abdullah, et al.
Publicado: (2020)

969. GRP78 and Integrin β1/α3 Play Disparate Roles in Epithelium Invasion During Mucormycosis
por: Alqarihi, Abdullah, et al.
Publicado: (2018)

Global proteomic analysis deciphers the mechanism of action of plant derived oleic acid against Candida albicans virulence and biofilm formation
por: Muthamil, Subramanian, et al.
Publicado: (2020)

Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis
por: Uppuluri, Priya, et al.
Publicado: (2018)

Human Serum Promotes Candida albicans Biofilm Growth and Virulence Gene Expression on Silicone Biomaterial
por: Samaranayake, Yuthika Hemamala, et al.
Publicado: (2013)

Tetracycline Effects on Candida Albicans Virulence Factors
por: McCool, Logan, et al.
Publicado: (2008)

Mucins Suppress Virulence Traits of Candida albicans
por: Kavanaugh, Nicole L., et al.
Publicado: (2014)

Recent advances on Candida albicans biology and virulence
por: Sellam, Adnane, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_8cr6il2a1rd92lsaqiqk6fjdjn