Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

There are currently limited Food and Drug Administration (FDA)-approved drugs and vaccines for the treatment or prevention of Coronavirus Disease 2019 (COVID-19). Enhanced understanding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and pathogenesis is critical for the dev...

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Detalles Bibliográficos
Autores principales: Ravindra, Neal G., Alfajaro, Mia Madel, Gasque, Victor, Huston, Nicholas C., Wan, Han, Szigeti-Buck, Klara, Yasumoto, Yuki, Greaney, Allison M., Habet, Victoria, Chow, Ryan D., Chen, Jennifer S., Wei, Jin, Filler, Renata B., Wang, Bao, Wang, Guilin, Niklason, Laura E., Montgomery, Ruth R., Eisenbarth, Stephanie C., Chen, Sidi, Williams, Adam, Iwasaki, Akiko, Horvath, Tamas L., Foxman, Ellen F., Pierce, Richard W., Pyle, Anna Marie, van Dijk, David, Wilen, Craig B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007021/
https://www.ncbi.nlm.nih.gov/pubmed/33730024
http://dx.doi.org/10.1371/journal.pbio.3001143

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