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CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...

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Detalles Bibliográficos
Autores principales:	Thanee, Malinee, Dokduang, Hasaya, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Klanrit, Poramate, Titapun, Attapol, Namwat, Nisana, Khuntikeo, Narong, Wangwiwatsin, Arporn, Saya, Hideyuki, Loilome, Watcharin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007026/ https://www.ncbi.nlm.nih.gov/pubmed/33780455 http://dx.doi.org/10.1371/journal.pone.0245871

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