GLRX3 Acts as a [2Fe–2S] Cluster Chaperone in the Cytosolic Iron–Sulfur Assembly Machinery Transferring [2Fe–2S] Clusters to NUBP1

[Image: see text] Human cytosolic monothiol glutaredoxin-3 (GLRX3) is a protein essential for the maturation of cytosolic [4Fe–4S] proteins. We show here that dimeric cluster-bridged GLRX3 transfers its [2Fe–2S](2+) clusters to the human P-loop NTPase NUBP1, an essential early component of the cytos...

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Detalles Bibliográficos
Autores principales: Camponeschi, Francesca, Prusty, Nihar Ranjan, Heider, Sabine Annemarie Elisabeth, Ciofi-Baffoni, Simone, Banci, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007109/
https://www.ncbi.nlm.nih.gov/pubmed/32429669
http://dx.doi.org/10.1021/jacs.0c02266

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