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Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples
We analyzed feasibility of pooling saliva samples for severe acute respiratory syndrome coronavirus 2 testing and found that sensitivity decreased according to pool size: 5 samples/pool, 7.4% reduction; 10 samples/pool, 11.1%; and 20 samples/pool, 14.8%. When virus prevalence is >2.6%, pools of 5...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Centers for Disease Control and Prevention
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007323/ https://www.ncbi.nlm.nih.gov/pubmed/33755009 http://dx.doi.org/10.3201/eid2704.204200 |
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| author | Watkins, Anne E. Fenichel, Eli P. Weinberger, Daniel M. Vogels, Chantal B.F. Brackney, Doug E. Casanovas-Massana, Arnau Campbell, Melissa Fournier, John Bermejo, Santos Datta, Rupak Dela Cruz, Charles S. Farhadian, Shelli F. Iwasaki, Akiko Ko, Albert I. Grubaugh, Nathan D. Wyllie, Anne L. |
| author_facet | Watkins, Anne E. Fenichel, Eli P. Weinberger, Daniel M. Vogels, Chantal B.F. Brackney, Doug E. Casanovas-Massana, Arnau Campbell, Melissa Fournier, John Bermejo, Santos Datta, Rupak Dela Cruz, Charles S. Farhadian, Shelli F. Iwasaki, Akiko Ko, Albert I. Grubaugh, Nathan D. Wyllie, Anne L. |
| author_sort | Watkins, Anne E. |
| collection | PubMed |
| description | We analyzed feasibility of pooling saliva samples for severe acute respiratory syndrome coronavirus 2 testing and found that sensitivity decreased according to pool size: 5 samples/pool, 7.4% reduction; 10 samples/pool, 11.1%; and 20 samples/pool, 14.8%. When virus prevalence is >2.6%, pools of 5 require fewer tests; when <0.6%, pools of 20 support screening strategies. |
| format | Online Article Text |
| id | pubmed-8007323 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Centers for Disease Control and Prevention |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-80073232021-04-06 Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples Watkins, Anne E. Fenichel, Eli P. Weinberger, Daniel M. Vogels, Chantal B.F. Brackney, Doug E. Casanovas-Massana, Arnau Campbell, Melissa Fournier, John Bermejo, Santos Datta, Rupak Dela Cruz, Charles S. Farhadian, Shelli F. Iwasaki, Akiko Ko, Albert I. Grubaugh, Nathan D. Wyllie, Anne L. Emerg Infect Dis Dispatch We analyzed feasibility of pooling saliva samples for severe acute respiratory syndrome coronavirus 2 testing and found that sensitivity decreased according to pool size: 5 samples/pool, 7.4% reduction; 10 samples/pool, 11.1%; and 20 samples/pool, 14.8%. When virus prevalence is >2.6%, pools of 5 require fewer tests; when <0.6%, pools of 20 support screening strategies. Centers for Disease Control and Prevention 2021-04 /pmc/articles/PMC8007323/ /pubmed/33755009 http://dx.doi.org/10.3201/eid2704.204200 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| spellingShingle | Dispatch Watkins, Anne E. Fenichel, Eli P. Weinberger, Daniel M. Vogels, Chantal B.F. Brackney, Doug E. Casanovas-Massana, Arnau Campbell, Melissa Fournier, John Bermejo, Santos Datta, Rupak Dela Cruz, Charles S. Farhadian, Shelli F. Iwasaki, Akiko Ko, Albert I. Grubaugh, Nathan D. Wyllie, Anne L. Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title | Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title_full | Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title_fullStr | Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title_full_unstemmed | Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title_short | Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples |
| title_sort | increased sars-cov-2 testing capacity with pooled saliva samples |
| topic | Dispatch |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007323/ https://www.ncbi.nlm.nih.gov/pubmed/33755009 http://dx.doi.org/10.3201/eid2704.204200 |
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