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A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions
METHODS: Twenty-six patients with UGI-SELs indicated for EUS-FNA were randomly assigned to the dry-first arm using the dry technique for the first two passes or the wet-first arm using the wet technique for the first two passes using a cross-over design with a ratio of 1 : 1. The primary endpoint wa...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007354/ https://www.ncbi.nlm.nih.gov/pubmed/33824658 http://dx.doi.org/10.1155/2021/4913107 |
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author | Takasumi, Mika Hikichi, Takuto Hashimoto, Minami Nakamura, Jun Kato, Tsunetaka Kikuchi, Hitomi Waragai, Yuichi Watanabe, Ko Takagi, Tadayuki Suzuki, Rei Sugimoto, Mitsuru Hayashi, Manabu Sato, Yuki Irie, Hiroki Kobashi, Ryoichiro Okubo, Yoshinori Kobayakawa, Masao Ohira, Hiromasa |
author_facet | Takasumi, Mika Hikichi, Takuto Hashimoto, Minami Nakamura, Jun Kato, Tsunetaka Kikuchi, Hitomi Waragai, Yuichi Watanabe, Ko Takagi, Tadayuki Suzuki, Rei Sugimoto, Mitsuru Hayashi, Manabu Sato, Yuki Irie, Hiroki Kobashi, Ryoichiro Okubo, Yoshinori Kobayakawa, Masao Ohira, Hiromasa |
author_sort | Takasumi, Mika |
collection | PubMed |
description | METHODS: Twenty-six patients with UGI-SELs indicated for EUS-FNA were randomly assigned to the dry-first arm using the dry technique for the first two passes or the wet-first arm using the wet technique for the first two passes using a cross-over design with a ratio of 1 : 1. The primary endpoint was the cellularity score of the EUS-FNA specimens rated on a 4-point scale (0-3). The secondary endpoints were the factors influencing cellularity in each suction technique. RESULTS: The mean cellularity score was 1.65 ± 1.20 for the wet technique and 2.00 ± 0.98 for the dry technique (p = 0.068). Logistic regression analysis showed that higher cellularity may be related to the final diagnosis of gastrointestinal stromal tumors in the dry technique and the SEL location in the upper stomach in the wet technique. CONCLUSION: The wet EUS-FNA technique failed to show a potential for improved cellularity of specimens compared to the dry technique for UGI-SELs. |
format | Online Article Text |
id | pubmed-8007354 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-80073542021-04-05 A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions Takasumi, Mika Hikichi, Takuto Hashimoto, Minami Nakamura, Jun Kato, Tsunetaka Kikuchi, Hitomi Waragai, Yuichi Watanabe, Ko Takagi, Tadayuki Suzuki, Rei Sugimoto, Mitsuru Hayashi, Manabu Sato, Yuki Irie, Hiroki Kobashi, Ryoichiro Okubo, Yoshinori Kobayakawa, Masao Ohira, Hiromasa Gastroenterol Res Pract Research Article METHODS: Twenty-six patients with UGI-SELs indicated for EUS-FNA were randomly assigned to the dry-first arm using the dry technique for the first two passes or the wet-first arm using the wet technique for the first two passes using a cross-over design with a ratio of 1 : 1. The primary endpoint was the cellularity score of the EUS-FNA specimens rated on a 4-point scale (0-3). The secondary endpoints were the factors influencing cellularity in each suction technique. RESULTS: The mean cellularity score was 1.65 ± 1.20 for the wet technique and 2.00 ± 0.98 for the dry technique (p = 0.068). Logistic regression analysis showed that higher cellularity may be related to the final diagnosis of gastrointestinal stromal tumors in the dry technique and the SEL location in the upper stomach in the wet technique. CONCLUSION: The wet EUS-FNA technique failed to show a potential for improved cellularity of specimens compared to the dry technique for UGI-SELs. Hindawi 2021-03-22 /pmc/articles/PMC8007354/ /pubmed/33824658 http://dx.doi.org/10.1155/2021/4913107 Text en Copyright © 2021 Mika Takasumi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Takasumi, Mika Hikichi, Takuto Hashimoto, Minami Nakamura, Jun Kato, Tsunetaka Kikuchi, Hitomi Waragai, Yuichi Watanabe, Ko Takagi, Tadayuki Suzuki, Rei Sugimoto, Mitsuru Hayashi, Manabu Sato, Yuki Irie, Hiroki Kobashi, Ryoichiro Okubo, Yoshinori Kobayakawa, Masao Ohira, Hiromasa A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title | A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title_full | A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title_fullStr | A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title_full_unstemmed | A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title_short | A Pilot Randomized Crossover Trial of Wet Suction and Conventional Techniques of Endoscopic Ultrasound-Guided Fine-Needle Aspiration for Upper Gastrointestinal Subepithelial Lesions |
title_sort | pilot randomized crossover trial of wet suction and conventional techniques of endoscopic ultrasound-guided fine-needle aspiration for upper gastrointestinal subepithelial lesions |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007354/ https://www.ncbi.nlm.nih.gov/pubmed/33824658 http://dx.doi.org/10.1155/2021/4913107 |
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