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Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity
BACKGROUND/OBJECTIVES: The branched-chain amino acids (BCAA), including isoleucine, leucine, and valine, promote muscle protein synthesis. However, obesity may interfere with protein synthesis by dysregulating mitochondrial function in the muscles. This study aimed to examine the association between...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Nutrition Society and the Korean Society of Community Nutrition
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007411/ https://www.ncbi.nlm.nih.gov/pubmed/33841724 http://dx.doi.org/10.4162/nrp.2021.15.2.203 |
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author | Chae, Minjeong Park, Hyoung Su Park, Kyong |
author_facet | Chae, Minjeong Park, Hyoung Su Park, Kyong |
author_sort | Chae, Minjeong |
collection | PubMed |
description | BACKGROUND/OBJECTIVES: The branched-chain amino acids (BCAA), including isoleucine, leucine, and valine, promote muscle protein synthesis. However, obesity may interfere with protein synthesis by dysregulating mitochondrial function in the muscles. This study aimed to examine the association between dietary intake levels of BCAA and skeletal muscle mass index (SMI) in middle-aged participants, and the effect of obesity/abdominal obesity on this association. SUBJECTS/METHODS: The data of 3,966 men and women aged 50–64 years who participated in the 2008–2011 Korea National Health and Nutrition Examination Survey were analyzed. Intake levels of energy-adjusted dietary amino acids were obtained using a 24-hour dietary recall. SMI was calculated by dividing the appendicular skeletal muscle mass by body weight (kg) and multiplying the result by 100%. Multivariable general linear models were used to analyze the association of dietary BCAA intake levels with SMI. RESULTS: The beneficial effects of energy-adjusted dietary BCAA intakes on SMI were greater in the non-obesity/non-abdominal obesity groups; however, no significant associations were observed in the obesity/abdominal obesity groups (P > 0.05). CONCLUSIONS: Healthy weight and sufficient intake of dietary BCAA are recommended to maintain muscle mass. |
format | Online Article Text |
id | pubmed-8007411 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Nutrition Society and the Korean Society of Community Nutrition |
record_format | MEDLINE/PubMed |
spelling | pubmed-80074112021-04-08 Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity Chae, Minjeong Park, Hyoung Su Park, Kyong Nutr Res Pract Original Research BACKGROUND/OBJECTIVES: The branched-chain amino acids (BCAA), including isoleucine, leucine, and valine, promote muscle protein synthesis. However, obesity may interfere with protein synthesis by dysregulating mitochondrial function in the muscles. This study aimed to examine the association between dietary intake levels of BCAA and skeletal muscle mass index (SMI) in middle-aged participants, and the effect of obesity/abdominal obesity on this association. SUBJECTS/METHODS: The data of 3,966 men and women aged 50–64 years who participated in the 2008–2011 Korea National Health and Nutrition Examination Survey were analyzed. Intake levels of energy-adjusted dietary amino acids were obtained using a 24-hour dietary recall. SMI was calculated by dividing the appendicular skeletal muscle mass by body weight (kg) and multiplying the result by 100%. Multivariable general linear models were used to analyze the association of dietary BCAA intake levels with SMI. RESULTS: The beneficial effects of energy-adjusted dietary BCAA intakes on SMI were greater in the non-obesity/non-abdominal obesity groups; however, no significant associations were observed in the obesity/abdominal obesity groups (P > 0.05). CONCLUSIONS: Healthy weight and sufficient intake of dietary BCAA are recommended to maintain muscle mass. The Korean Nutrition Society and the Korean Society of Community Nutrition 2021-04 2020-11-30 /pmc/articles/PMC8007411/ /pubmed/33841724 http://dx.doi.org/10.4162/nrp.2021.15.2.203 Text en ©2021 The Korean Nutrition Society and the Korean Society of Community Nutrition https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Chae, Minjeong Park, Hyoung Su Park, Kyong Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title | Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title_full | Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title_fullStr | Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title_full_unstemmed | Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title_short | Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity |
title_sort | association between dietary branched-chain amino acid intake and skeletal muscle mass index among korean adults: interaction with obesity |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007411/ https://www.ncbi.nlm.nih.gov/pubmed/33841724 http://dx.doi.org/10.4162/nrp.2021.15.2.203 |
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