Cargando…

Inhibition of Long Noncoding RNA SNHG15 Ameliorates Hypoxia/Ischemia-Induced Neuronal Damage by Regulating miR-302a-3p/STAT1/NF-κB Axis

PURPOSE: Ischemic brain injury results in high mortality and serious neurologic morbidity. Here, we explored the role of SNHG15 in modulating neuronal damage and microglial inflammation after ischemia stroke. MATERIALS AND METHODS: The hypoxia/ischemia models were induced by middle cerebral artery o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Chunting, Li, Chen, Ma, Qiaoya, Wang, Ruili, He, Ya, Wang, Hui, Luo, Guogang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Yonsei University College of Medicine 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007436/ https://www.ncbi.nlm.nih.gov/pubmed/33779086 http://dx.doi.org/10.3349/ymj.2021.62.4.325

Ejemplares similares

Retraction: Paper “Inhibition of Long Noncoding RNA SNHG15 Ameliorates Hypoxia/Ischemia-Induced Neuronal Damage by Regulating miR-302a-3p/STAT1/NF-κB Axis” by Hu C, et al. [Yonsei Med J 2021;62(4):325-337]
Publicado: (2022)

PIAS3 suppresses damage in an Alzheimer’s disease cell model by inducing the STAT3-associated STAT3/Nestin/Nrf2/HO-1 pathway
por: Li, Chen, et al.
Publicado: (2021)

Dexmedetomidine attenuates the neuroinflammation and cognitive dysfunction in aged mice by targeting the SNHG14/miR‑340/NF‑κB axis
por: He, Guangbao, et al.
Publicado: (2023)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
por: Lee, Wonhwa, et al.
Publicado: (2020)

The Hypoxia-Activated Prodrug TH-302: Exploiting Hypoxia in Cancer Therapy
por: Li, Yue, et al.
Publicado: (2021)

Regulation of Microglia-Activation-Mediated Neuroinflammation to Ameliorate Ischemia-Reperfusion Injury via the STAT5-NF-κB Pathway in Ischemic Stroke
por: Pu, Zhijun, et al.
Publicado: (2022)

Silence of Long Noncoding RNA SNHG14 Alleviates Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating miR-124-3p/MMP2 Axis
por: Xue, Qianlong, et al.
Publicado: (2021)

LncRNA SNHG16 contributes to tumor progression via the miR-302b-3p/SLC2A4 axis in pancreatic adenocarcinoma
por: Xu, Hao, et al.
Publicado: (2021)

Long noncoding RNA SNHG6 silencing sensitized esophageal cancer cells to 5-FU via EZH2/STAT pathway
por: Tan, Ran, et al.
Publicado: (2023)

Hypoxia Induced NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2016)

Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA-124 and thereby upregulating STAT3
por: Sun, Xiaowen, et al.
Publicado: (2020)

Long noncoding RNA SNHG14 promotes the aggressiveness of retinoblastoma by sponging microRNA-124 and thereby upregulating STAT3
por: Sun, Xiaowen, et al.
Publicado: (2022)

Long noncoding RNA SNHG17: a novel molecule in human cancers
por: Ma, Li, et al.
Publicado: (2022)

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
por: Chen, Xiao-Wu, et al.
Publicado: (2015)

Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice
por: Zhang, Peng, et al.
Publicado: (2023)

Long noncoding RNA SNHG15: A promising target in human cancers
por: Zhang, Niu, et al.
Publicado: (2023)

Shenlian Extract Against Myocardial Injury Induced by Ischemia Through the Regulation of NF-κB/IκB Signaling Axis
por: Guo, Yuan, et al.
Publicado: (2020)

Long noncoding RNA SNHG4: a novel target in human diseases
por: Chu, Qingfei, et al.
Publicado: (2021)

Pyruvate sensitizes pancreatic tumors to hypoxia-activated prodrug TH-302
por: Wojtkowiak, Jonathan W, et al.
Publicado: (2015)

SNHG15: a promising cancer-related long noncoding RNA
por: Tong, Jinfei, et al.
Publicado: (2019)

The role of long noncoding RNA SNHG7 in human cancers (Review)
por: Bian, Zheng, et al.
Publicado: (2020)

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease
por: de Gregorio, Estefanía, et al.
Publicado: (2020)

Resmetirom Ameliorates NASH-Model Mice by Suppressing STAT3 and NF-κB Signaling Pathways in an RGS5-Dependent Manner
por: Wang, Xiaojing, et al.
Publicado: (2023)

Long Noncoding RNA SNHG1 Knockdown Ameliorates Apoptosis, Oxidative Stress and Inflammation in Models of Parkinson’s Disease by Inhibiting the miR-125b-5p/MAPK1 Axis
por: Xiao, Xiao, et al.
Publicado: (2021)

LncRNA SNHG10 suppresses the development of doxorubicin resistance by downregulating miR-302b in triple-negative breast cancer
por: Aini, Shataer, et al.
Publicado: (2022)

The Long Noncoding RNA MAGI1-IT1 Regulates the miR-302d-3p/IGF1 Axis to Control Gastric Cancer Cell Proliferation
por: Wang, Qinge, et al.
Publicado: (2021)

Lnc-SNHG5 Promoted Hepatocellular Carcinoma Progression Through the RPS3-NFκB Pathway
por: Hao, Jie, et al.
Publicado: (2023)

Pioglitazone Ameliorates Renal Ischemia-Reperfusion Injury via Inhibition of NF-κB Activation and Inflammation in Rats
por: Zou, Gaode, et al.
Publicado: (2021)

Long noncoding RNA SNHG4 promotes the malignant progression of hepatocellular carcinoma through the miR‐211‐5p/CREB5 axis
por: Qiu, Jiannan, et al.
Publicado: (2022)

Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways
por: Jia, Yan, et al.
Publicado: (2011)

Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302
por: Lohse, Ines, et al.
Publicado: (2016)

Metformin Attenuates Ischemia-reperfusion Injury of Fatty Liver in Rats Through Inhibition of the TLR4/NF-κB Axis
por: Li, Xiaohua, et al.
Publicado: (2020)

Long noncoding RNA SNHG12 is a potential diagnostic and prognostic biomarker in various tumors
por: Wang, Xinzhuang, et al.
Publicado: (2021)

Upregulation of the Long Noncoding RNA SNHG3 Promotes Lung Adenocarcinoma Proliferation
por: Liu, Liang, et al.
Publicado: (2018)

Long Noncoding RNA SNHG16 Facilitates Abdominal Aortic Aneurysm Progression through the miR-106b-5p/STAT3 Feedback Loop
por: Yang, Baihui, et al.
Publicado: (2021)

Augmenter of liver regeneration ameliorates ischemia-reperfusion injury in steatotic liver via inhibition of the TLR4/NF-κB pathway
por: Weng, Junhua, et al.
Publicado: (2021)

Knockdown of SNHG15 suppresses renal cell carcinoma proliferation and EMT by regulating the NF-κB signaling pathway
por: Du, Yang, et al.
Publicado: (2022)

Enhancement of hypoxia-activated prodrug TH-302 anti-tumor activity by Chk1 inhibition
por: Meng, Fanying, et al.
Publicado: (2015)

Long Noncoding RNA SNHG4 Attenuates the Injury of Myocardial Infarction via Regulating miR-148b-3p/DUSP1 Axis
por: Wang, Sheng, et al.
Publicado: (2022)

Hypoxia-Targeting Drug Evofosfamide (TH-302) Enhances Sunitinib Activity in Neuroblastoma Xenograft Models()
por: Kumar, Sushil, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_046do0si4alqlngvv6kbg7vf1t