Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region

INTRODUCTION: Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated. CASE REPORT: We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for lo...

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Detalles Bibliográficos
Autores principales: De Felice, Francesca, Musio, Daniela, Tombolini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2020
Materias:
Radiotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007498/
https://www.ncbi.nlm.nih.gov/pubmed/33058025
http://dx.doi.org/10.1007/s11547-020-01260-5
Descripción
Sumario:INTRODUCTION: Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated. CASE REPORT: We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for locally advanced inoperable disease. RESULTS: Weekly hypofractionated radiotherapy assured complete regression and was well-tolerated. CONCLUSION: The real efficacy of this treatment in the therapeutic arsenal remains to be defined. A clinical trial is ongoing to test the use of 8 weekly fractions of 8 Gy hypofractionated RT regimens in non-resectable cSCC cases.

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