Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region

INTRODUCTION: Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated. CASE REPORT: We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for lo...

Descripción completa

Detalles Bibliográficos
Autores principales: De Felice, Francesca, Musio, Daniela, Tombolini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2020
Materias:
Radiotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007498/
https://www.ncbi.nlm.nih.gov/pubmed/33058025
http://dx.doi.org/10.1007/s11547-020-01260-5
_version_ 1783672502165176320
author De Felice, Francesca
Musio, Daniela
Tombolini, Vincenzo
author_facet De Felice, Francesca
Musio, Daniela
Tombolini, Vincenzo
author_sort De Felice, Francesca
collection PubMed
description INTRODUCTION: Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated. CASE REPORT: We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for locally advanced inoperable disease. RESULTS: Weekly hypofractionated radiotherapy assured complete regression and was well-tolerated. CONCLUSION: The real efficacy of this treatment in the therapeutic arsenal remains to be defined. A clinical trial is ongoing to test the use of 8 weekly fractions of 8 Gy hypofractionated RT regimens in non-resectable cSCC cases.
format Online
Article
Text
id pubmed-8007498
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Milan
record_format MEDLINE/PubMed
spelling pubmed-80074982021-04-16 Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region De Felice, Francesca Musio, Daniela Tombolini, Vincenzo Radiol Med Radiotherapy INTRODUCTION: Treatment of inoperable cutaneous squamous cell carcinoma (cSCC) of the head and neck region is still debated. CASE REPORT: We report an original case of cure of cSCC of the head and neck region with weekly hypofractionated radiation therapy with megavoltage electrons prescribed for locally advanced inoperable disease. RESULTS: Weekly hypofractionated radiotherapy assured complete regression and was well-tolerated. CONCLUSION: The real efficacy of this treatment in the therapeutic arsenal remains to be defined. A clinical trial is ongoing to test the use of 8 weekly fractions of 8 Gy hypofractionated RT regimens in non-resectable cSCC cases. Springer Milan 2020-10-15 2021 /pmc/articles/PMC8007498/ /pubmed/33058025 http://dx.doi.org/10.1007/s11547-020-01260-5 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Radiotherapy
De Felice, Francesca
Musio, Daniela
Tombolini, Vincenzo
Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title_full Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title_fullStr Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title_full_unstemmed Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title_short Weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
title_sort weekly hypofractionated radiation therapy in elderly non-resectable cutaneous squamous cell carcinoma of the head and neck region
topic Radiotherapy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007498/
https://www.ncbi.nlm.nih.gov/pubmed/33058025
http://dx.doi.org/10.1007/s11547-020-01260-5
work_keys_str_mv AT defelicefrancesca weeklyhypofractionatedradiationtherapyinelderlynonresectablecutaneoussquamouscellcarcinomaoftheheadandneckregion
AT musiodaniela weeklyhypofractionatedradiationtherapyinelderlynonresectablecutaneoussquamouscellcarcinomaoftheheadandneckregion
AT tombolinivincenzo weeklyhypofractionatedradiationtherapyinelderlynonresectablecutaneoussquamouscellcarcinomaoftheheadandneckregion

Ejemplares similares