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Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System

Recently, there has been an incredible increase in research about the abnormal growth of cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It has been understood that the natural defense system, composed of a variety of immune defensive cells, does not just limit i...

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Autores principales: Muluh, Tobias Achu, Chen, Zhuo, Li, Yi, Xiong, Kang, Jin, Jing, Fu, ShaoZhi, Wu, JingBo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007559/
https://www.ncbi.nlm.nih.gov/pubmed/33790556
http://dx.doi.org/10.2147/IJN.S295300
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author Muluh, Tobias Achu
Chen, Zhuo
Li, Yi
Xiong, Kang
Jin, Jing
Fu, ShaoZhi
Wu, JingBo
author_facet Muluh, Tobias Achu
Chen, Zhuo
Li, Yi
Xiong, Kang
Jin, Jing
Fu, ShaoZhi
Wu, JingBo
author_sort Muluh, Tobias Achu
collection PubMed
description Recently, there has been an incredible increase in research about the abnormal growth of cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It has been understood that the natural defense system, composed of a variety of immune defensive cells, does not just limit its function in eliminating neoplastic cells, but also controls the growth and spread of tumor cells of different kinds to other parts of the body. Cancer immunotherapy, is a cancer treatment plan that educates the body’s defensive system to forestall, control, and eliminate tumor cells. The effectiveness of immunotherapy is achieved, to its highest efficacy, by the use of nanoparticles (NPs) for precise and timely delivery of immunotherapies to specific targeted neoplasms, with less or no harm to the healthy cells. Immunotherapies have been affirmed in clinical trials as a cancer regimen for various types of cancers, the side effects resulting from imprecise and non-targeted conveyance is well managed with the use of nanoparticles. Nonetheless, we will concentrate on enhancing cancer immunotherapy approaches by the use of nanoparticles for the productivity of antitumor immunity. Nanoparticles will be presented and utilized as an objective immunotherapy delivery system for high exactness and are thus a promising methodology for cancer treatment.
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spelling pubmed-80075592021-03-30 Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System Muluh, Tobias Achu Chen, Zhuo Li, Yi Xiong, Kang Jin, Jing Fu, ShaoZhi Wu, JingBo Int J Nanomedicine Review Recently, there has been an incredible increase in research about the abnormal growth of cells (neoplasm), focusing on the management, treatment and preventing reoccurrence. It has been understood that the natural defense system, composed of a variety of immune defensive cells, does not just limit its function in eliminating neoplastic cells, but also controls the growth and spread of tumor cells of different kinds to other parts of the body. Cancer immunotherapy, is a cancer treatment plan that educates the body’s defensive system to forestall, control, and eliminate tumor cells. The effectiveness of immunotherapy is achieved, to its highest efficacy, by the use of nanoparticles (NPs) for precise and timely delivery of immunotherapies to specific targeted neoplasms, with less or no harm to the healthy cells. Immunotherapies have been affirmed in clinical trials as a cancer regimen for various types of cancers, the side effects resulting from imprecise and non-targeted conveyance is well managed with the use of nanoparticles. Nonetheless, we will concentrate on enhancing cancer immunotherapy approaches by the use of nanoparticles for the productivity of antitumor immunity. Nanoparticles will be presented and utilized as an objective immunotherapy delivery system for high exactness and are thus a promising methodology for cancer treatment. Dove 2021-03-25 /pmc/articles/PMC8007559/ /pubmed/33790556 http://dx.doi.org/10.2147/IJN.S295300 Text en © 2021 Muluh et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Muluh, Tobias Achu
Chen, Zhuo
Li, Yi
Xiong, Kang
Jin, Jing
Fu, ShaoZhi
Wu, JingBo
Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_full Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_fullStr Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_full_unstemmed Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_short Enhancing Cancer Immunotherapy Treatment Goals by Using Nanoparticle Delivery System
title_sort enhancing cancer immunotherapy treatment goals by using nanoparticle delivery system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007559/
https://www.ncbi.nlm.nih.gov/pubmed/33790556
http://dx.doi.org/10.2147/IJN.S295300
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