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MiR-199-3p enhances muscle regeneration and ameliorates aged muscle and muscular dystrophy
Parabiosis experiments suggest that molecular factors related to rejuvenation and aging circulate in the blood. Here, we show that miR-199-3p, which circulates in the blood as a cell-free miRNA, is significantly decreased in the blood of aged mice compared to young mice; and miR-199-3p has the abili...
Autores principales: | Fukuoka, Masashi, Fujita, Hiromi, Numao, Kosumo, Nakamura, Yasuko, Shimizu, Hideo, Sekiguchi, Masayuki, Hohjoh, Hirohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007565/ https://www.ncbi.nlm.nih.gov/pubmed/33782502 http://dx.doi.org/10.1038/s42003-021-01952-2 |
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