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Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material

This paper reports about the outcomes from an investigation carried out on tunable biosensor for detection using infrared in the range of 1.5 µm and 1.65 µm. The biosensor is made of phase change material formed by different alloy combinations, Ge(2)Sb(2)Te(5) (GST). The nature of GST allows for the...

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Autores principales: Patel, Shobhit K., Parmar, Juveriya, Sorathiya, Vishal, Nguyen, Truong Khang, Dhasarathan, Vigneswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007597/
https://www.ncbi.nlm.nih.gov/pubmed/33782516
http://dx.doi.org/10.1038/s41598-021-86700-6
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author Patel, Shobhit K.
Parmar, Juveriya
Sorathiya, Vishal
Nguyen, Truong Khang
Dhasarathan, Vigneswaran
author_facet Patel, Shobhit K.
Parmar, Juveriya
Sorathiya, Vishal
Nguyen, Truong Khang
Dhasarathan, Vigneswaran
author_sort Patel, Shobhit K.
collection PubMed
description This paper reports about the outcomes from an investigation carried out on tunable biosensor for detection using infrared in the range of 1.5 µm and 1.65 µm. The biosensor is made of phase change material formed by different alloy combinations, Ge(2)Sb(2)Te(5) (GST). The nature of GST allows for the material to change phase with changes in temperature, giving the tunable sensing property for biosensing application. Sensor built with amorphous GST (aGST) and crystalline GST (cGST) in different design structures were tested on different concentrations of biomolecules: hemoglobin (10 g/l, 20 g/l, 30 g/l and 40 g/l); and urine (0–1.5 mg/dL, 2.5 mg/dL, 5 mg/dL and 10 mg/dL). The tunable response observed from the tests demonstrates the potential application of the materials in the design of switching and sensing systems.
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spelling pubmed-80075972021-03-30 Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material Patel, Shobhit K. Parmar, Juveriya Sorathiya, Vishal Nguyen, Truong Khang Dhasarathan, Vigneswaran Sci Rep Article This paper reports about the outcomes from an investigation carried out on tunable biosensor for detection using infrared in the range of 1.5 µm and 1.65 µm. The biosensor is made of phase change material formed by different alloy combinations, Ge(2)Sb(2)Te(5) (GST). The nature of GST allows for the material to change phase with changes in temperature, giving the tunable sensing property for biosensing application. Sensor built with amorphous GST (aGST) and crystalline GST (cGST) in different design structures were tested on different concentrations of biomolecules: hemoglobin (10 g/l, 20 g/l, 30 g/l and 40 g/l); and urine (0–1.5 mg/dL, 2.5 mg/dL, 5 mg/dL and 10 mg/dL). The tunable response observed from the tests demonstrates the potential application of the materials in the design of switching and sensing systems. Nature Publishing Group UK 2021-03-29 /pmc/articles/PMC8007597/ /pubmed/33782516 http://dx.doi.org/10.1038/s41598-021-86700-6 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Patel, Shobhit K.
Parmar, Juveriya
Sorathiya, Vishal
Nguyen, Truong Khang
Dhasarathan, Vigneswaran
Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title_full Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title_fullStr Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title_full_unstemmed Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title_short Tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
title_sort tunable infrared metamaterial-based biosensor for detection of hemoglobin and urine using phase change material
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007597/
https://www.ncbi.nlm.nih.gov/pubmed/33782516
http://dx.doi.org/10.1038/s41598-021-86700-6
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