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Structural and functional analysis of LIM domain-dependent recruitment of paxillin to αvβ3 integrin-positive focal adhesions
The LIM domain-dependent localization of the adapter protein paxillin to β3 integrin-positive focal adhesions (FAs) is not mechanistically understood. Here, by combining molecular biology, photoactivation and FA-isolation experiments, we demonstrate specific contributions of each LIM domain of paxil...
Autores principales: | Ripamonti, Marta, Liaudet, Nicolas, Azizi, Latifeh, Bouvard, Daniel, Hytönen, Vesa P., Wehrle-Haller, Bernhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007706/ https://www.ncbi.nlm.nih.gov/pubmed/33782527 http://dx.doi.org/10.1038/s42003-021-01886-9 |
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