Cargando…

Ahi1 regulates the nuclear translocation of glucocorticoid receptor to modulate stress response

Stress activates the nuclear translocation of glucocorticoid receptors (GR) to trigger gene expression. Abnormal GR levels can alter the stress responses in animals and therapeutic effects of antidepressants. Here, we reported that stress-mediated nuclear translocation of GR reduced Ahi1 in the stre...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Bin, Xin, Ning, Qian, Xuanchen, Zhai, Lijing, Miao, Zhigang, Yang, Yong, Li, Shihua, Sun, Miao, Xu, Xingshun, Li, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007735/
https://www.ncbi.nlm.nih.gov/pubmed/33782379
http://dx.doi.org/10.1038/s41398-021-01305-x