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Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity
Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream. Lameness presentation, one of the primary consequences of ARA in cattle, is associated with the occurr...
Autores principales: | Quiroga, John, Alarcón, Pablo, Manosalva, Carolina, Teuber, Stefanie, Taubert, Anja, Hermosilla, Carlos, Hidalgo, María Angélica, Carretta, María Daniella, Burgos, Rafael Agustín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007789/ https://www.ncbi.nlm.nih.gov/pubmed/33796579 http://dx.doi.org/10.3389/fvets.2021.625347 |
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