Inhibiting CBX4 efficiently protects hepatocellular carcinoma cells against sorafenib resistance

BACKGROUND: This study aimed to investigate the possible role of inhibiting chromobox protein homologue 4 (CBX4) to deregulate of cancer stem cells (CSCs) and to evaluate the contribution of these molecules to sorafenib resistance in advanced hepatocellular carcinoma (HCC). METHODS: HCC cell lines a...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Ma, Bo, Tian, Zhihua, Han, Haibo, Tang, Jintian, Dong, Bin, An, Guo, Cao, Baoshan, Wang, Boqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007794/
https://www.ncbi.nlm.nih.gov/pubmed/33473171
http://dx.doi.org/10.1038/s41416-020-01240-6

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