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2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression

Background: 2-Methoxyestradiol (2ME), a natural 17-β estradiol metabolite, is a potent anti-inflammatory agent, but its effect on ischemia/reperfusion (IR)-induced acute lung inflammation remains unknown. Annexin A1 (AnxA1), a glucocorticoid-regulated protein, is effective at inhibiting neutrophil t...

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Detalles Bibliográficos
Autores principales: Liao, Wen-I, Wu, Shu-Yu, Tsai, Shih-Hung, Pao, Hsin-Ping, Huang, Kun-Lun, Chu, Shi-Jye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007881/
https://www.ncbi.nlm.nih.gov/pubmed/33796096
http://dx.doi.org/10.3389/fimmu.2021.596376