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2-Methoxyestradiol Protects Against Lung Ischemia/Reperfusion Injury by Upregulating Annexin A1 Protein Expression
Background: 2-Methoxyestradiol (2ME), a natural 17-β estradiol metabolite, is a potent anti-inflammatory agent, but its effect on ischemia/reperfusion (IR)-induced acute lung inflammation remains unknown. Annexin A1 (AnxA1), a glucocorticoid-regulated protein, is effective at inhibiting neutrophil t...
Autores principales: | Liao, Wen-I, Wu, Shu-Yu, Tsai, Shih-Hung, Pao, Hsin-Ping, Huang, Kun-Lun, Chu, Shi-Jye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007881/ https://www.ncbi.nlm.nih.gov/pubmed/33796096 http://dx.doi.org/10.3389/fimmu.2021.596376 |
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