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Impact of the Whole Genome Duplication Event on PYK Activity and Effects of a PYK1 Mutation on Metabolism in S. cerevisiae

Background: Evolution of aerobic fermentation (crabtree effect) in yeast is associated with the whole genome duplication (WGD) event, suggesting that duplication of certain genes may have altered yeast metabolism. The pyruvate kinase (PYK) gene is associated with alterations in cell metabolism, and...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Blum, Jamie E., Thalacker-Mercer, Anna, Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007964/
https://www.ncbi.nlm.nih.gov/pubmed/33796550
http://dx.doi.org/10.3389/fmolb.2021.656461