Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS

Zirconia nanoparticles (ZrO(2) NPs) are commonly used in the field of biomedical materials, but their antitumor activity and mechanism is unclear. Herein, we evaluated the anti-tumor activity of ZrO(2) NPs and explored the anti-tumor mechanism. The results of in vitro and in vivo experiments showed...

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Detalles Bibliográficos
Autores principales: Shang, Yinghui, Wang, Qinghai, Li, Jian, Liu, Haiting, Zhao, Qiangqiang, Huang, Xueyuan, Dong, Hang, Chen, Wansong, Gui, Rong, Nie, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8007972/
https://www.ncbi.nlm.nih.gov/pubmed/33796503
http://dx.doi.org/10.3389/fchem.2021.522708

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