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Protein kinase C fusion proteins are paradoxically loss of function in cancer

Within the AGC kinase superfamily, gene fusions resulting from chromosomal rearrangements have been most frequently described for protein kinase C (PKC), with gene fragments encoding either the C-terminal catalytic domain or the N-terminal regulatory moiety fused to other genes. Kinase fusions that...

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Detalles Bibliográficos
Autores principales:	Van, An-Angela N., Kunkel, Maya T., Baffi, Timothy R., Lordén, Gema, Antal, Corina E., Banerjee, Sourav, Newton, Alexandra C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008189/ https://www.ncbi.nlm.nih.gov/pubmed/33617877 http://dx.doi.org/10.1016/j.jbc.2021.100445

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