Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells

Use of immune checkpoint inhibitors (ICIs) with chemotherapy to enhance responses in oesophageal adenocarcinoma (OAC) is an attractive approach. We identified subpopulations of OAC cells expressing inhibitory immune checkpoint (IC) ligands (PD-L1, PD-L2 and CD160) and receptors (PD-1, TIGIT, TIM-3,...

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Detalles Bibliográficos
Autores principales: Davern, Maria, Donlon, Noel E., Sheppard, Andrew, Connell, Fiona O’, Hayes, Conall, Bhardwaj, Anshul, Foley, Emma, Toole, Dermot O’, Lynam-Lennon, Niamh, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Lysaght, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008239/
https://www.ncbi.nlm.nih.gov/pubmed/33765543
http://dx.doi.org/10.1016/j.tranon.2021.101062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8008239/
https://www.ncbi.nlm.nih.gov/pubmed/33765543
http://dx.doi.org/10.1016/j.tranon.2021.101062

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